-transparent.png){kind=logo}
A double-blind, crossover study was performed with a new topical aerosol steroid, flunisolide, administered every 12 hours over a period of eight weeks to 36 adult patients with perennial allergic rhinitis. During the treatment period the majority of patients had significant relief of symptoms as compared with the placebo period. Most prominent improvement occurred with the symptoms of nasal stuffiness, sneezing, rhinorrhea and the number of times patients had to blow their noses. Best results were obtained in patients with higher degrees of atopy. Side effects were minimal and limited to nasal irritation in some patients. Criteria for optimal patient selection are discussed and an explanation for the lack of systemic effects of aerosolized use of the newer corticosteroids is given.
F L Bloom, and
R H Cohan, and
K N Leifer, and
D L Spangler, and
R B Rhoades, and
H J Wittig
January 1995,
Pneumonologia i alergologia polska,
F L Bloom, and
R H Cohan, and
K N Leifer, and
D L Spangler, and
R B Rhoades, and
H J Wittig
April 1966,
Annals of allergy,
F L Bloom, and
R H Cohan, and
K N Leifer, and
D L Spangler, and
R B Rhoades, and
H J Wittig
August 1978,
Canadian Medical Association journal,
F L Bloom, and
R H Cohan, and
K N Leifer, and
D L Spangler, and
R B Rhoades, and
H J Wittig
November 1979,
Archives of otolaryngology (Chicago, Ill. : 1960),
F L Bloom, and
R H Cohan, and
K N Leifer, and
D L Spangler, and
R B Rhoades, and
H J Wittig
October 1983,
South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde,
F L Bloom, and
R H Cohan, and
K N Leifer, and
D L Spangler, and
R B Rhoades, and
H J Wittig
March 1979,
Annals of allergy,
F L Bloom, and
R H Cohan, and
K N Leifer, and
D L Spangler, and
R B Rhoades, and
H J Wittig
January 1980,
Clinical allergy,
F L Bloom, and
R H Cohan, and
K N Leifer, and
D L Spangler, and
R B Rhoades, and
H J Wittig
June 1977,
Archives of disease in childhood,
F L Bloom, and
R H Cohan, and
K N Leifer, and
D L Spangler, and
R B Rhoades, and
H J Wittig
July 1982,
Allergy,
F L Bloom, and
R H Cohan, and
K N Leifer, and
D L Spangler, and
R B Rhoades, and
H J Wittig
December 1946,
Canadian Medical Association journal,
