Dietary intake of calcium and postmenopausal bone loss. 1988

J C Stevenson, and M I Whitehead, and M Padwick, and J A Endacott, and C Sutton, and L M Banks, and C Freemantle, and T J Spinks, and R Hesp
Cavendish Clinic, London.

The use of calcium supplements to prevent postmenopausal bone loss and hence osteoporosis is widespread, but the evidence for their efficacy, either alone or in combination with other treatments, is contradictory. Skeletal measurements and dietary intake of calcium were determined in 59 healthy postmenopausal women, most of whom were within five years of the menopause. No correlation was found between current intake of calcium and either total calcium in the body or the density of trabecular or cortical bone in the forearm or vertebral trabecular bone. Dietary intake of calcium did not influence the rate of postmenopausal bone loss in the 54 women who completed 12 months of active or placebo treatment. Even when extremes of calcium intake were examined no difference was found in bone measurements between the women with the highest and lowest intakes. The results of this study suggest that the bone density of women in the early menopause is not influenced by current dietary intake of calcium.

UI MeSH Term Description Entries
D008593 Menopause The last menstrual period. Permanent cessation of menses (MENSTRUATION) is usually defined after 6 to 12 months of AMENORRHEA in a woman over 45 years of age. In the United States, menopause generally occurs in women between 48 and 55 years of age. Change of Life, Female
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D010024 Osteoporosis Reduction of bone mass without alteration in the composition of bone, leading to fractures. Primary osteoporosis can be of two major types: postmenopausal osteoporosis (OSTEOPOROSIS, POSTMENOPAUSAL) and age-related or senile osteoporosis. Age-Related Osteoporosis,Bone Loss, Age-Related,Osteoporosis, Age-Related,Osteoporosis, Post-Traumatic,Osteoporosis, Senile,Senile Osteoporosis,Osteoporosis, Involutional,Age Related Osteoporosis,Age-Related Bone Loss,Age-Related Bone Losses,Age-Related Osteoporoses,Bone Loss, Age Related,Bone Losses, Age-Related,Osteoporoses,Osteoporoses, Age-Related,Osteoporoses, Senile,Osteoporosis, Age Related,Osteoporosis, Post Traumatic,Post-Traumatic Osteoporoses,Post-Traumatic Osteoporosis,Senile Osteoporoses
D011897 Random Allocation A process involving chance used in therapeutic trials or other research endeavor for allocating experimental subjects, human or animal, between treatment and control groups, or among treatment groups. It may also apply to experiments on inanimate objects. Randomization,Allocation, Random
D001842 Bone and Bones A specialized CONNECTIVE TISSUE that is the main constituent of the SKELETON. The principal cellular component of bone is comprised of OSTEOBLASTS; OSTEOCYTES; and OSTEOCLASTS, while FIBRILLAR COLLAGENS and hydroxyapatite crystals form the BONE MATRIX. Bone Tissue,Bone and Bone,Bone,Bones,Bones and Bone,Bones and Bone Tissue,Bony Apophyses,Bony Apophysis,Condyle,Apophyses, Bony,Apophysis, Bony,Bone Tissues,Condyles,Tissue, Bone,Tissues, Bone
D002118 Calcium A basic element found in nearly all tissues. It is a member of the alkaline earth family of metals with the atomic symbol Ca, atomic number 20, and atomic weight 40. Calcium is the most abundant mineral in the body and combines with phosphorus to form calcium phosphate in the bones and teeth. It is essential for the normal functioning of nerves and muscles and plays a role in blood coagulation (as factor IV) and in many enzymatic processes. Coagulation Factor IV,Factor IV,Blood Coagulation Factor IV,Calcium-40,Calcium 40,Factor IV, Coagulation
D002136 Calcium, Dietary Calcium compounds in DIETARY SUPPLEMENTS or in food that supply the body with calcium. Dietary Calcium
D003430 Cross-Sectional Studies Studies in which the presence or absence of disease or other health-related variables are determined in each member of the study population or in a representative sample at one particular time. This contrasts with LONGITUDINAL STUDIES which are followed over a period of time. Disease Frequency Surveys,Prevalence Studies,Analysis, Cross-Sectional,Cross Sectional Analysis,Cross-Sectional Survey,Surveys, Disease Frequency,Analyses, Cross Sectional,Analyses, Cross-Sectional,Analysis, Cross Sectional,Cross Sectional Analyses,Cross Sectional Studies,Cross Sectional Survey,Cross-Sectional Analyses,Cross-Sectional Analysis,Cross-Sectional Study,Cross-Sectional Surveys,Disease Frequency Survey,Prevalence Study,Studies, Cross-Sectional,Studies, Prevalence,Study, Cross-Sectional,Study, Prevalence,Survey, Cross-Sectional,Survey, Disease Frequency,Surveys, Cross-Sectional
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man

Related Publications

J C Stevenson, and M I Whitehead, and M Padwick, and J A Endacott, and C Sutton, and L M Banks, and C Freemantle, and T J Spinks, and R Hesp
October 1987, The American journal of clinical nutrition,
J C Stevenson, and M I Whitehead, and M Padwick, and J A Endacott, and C Sutton, and L M Banks, and C Freemantle, and T J Spinks, and R Hesp
August 2019, The Journal of clinical endocrinology and metabolism,
J C Stevenson, and M I Whitehead, and M Padwick, and J A Endacott, and C Sutton, and L M Banks, and C Freemantle, and T J Spinks, and R Hesp
January 2020, The Journal of clinical endocrinology and metabolism,
J C Stevenson, and M I Whitehead, and M Padwick, and J A Endacott, and C Sutton, and L M Banks, and C Freemantle, and T J Spinks, and R Hesp
October 1987, The Journal of clinical investigation,
J C Stevenson, and M I Whitehead, and M Padwick, and J A Endacott, and C Sutton, and L M Banks, and C Freemantle, and T J Spinks, and R Hesp
May 2017, The British journal of nutrition,
J C Stevenson, and M I Whitehead, and M Padwick, and J A Endacott, and C Sutton, and L M Banks, and C Freemantle, and T J Spinks, and R Hesp
August 1988, BMJ (Clinical research ed.),
J C Stevenson, and M I Whitehead, and M Padwick, and J A Endacott, and C Sutton, and L M Banks, and C Freemantle, and T J Spinks, and R Hesp
September 2019, The Journal of clinical endocrinology and metabolism,
J C Stevenson, and M I Whitehead, and M Padwick, and J A Endacott, and C Sutton, and L M Banks, and C Freemantle, and T J Spinks, and R Hesp
January 1981, Ugeskrift for laeger,
J C Stevenson, and M I Whitehead, and M Padwick, and J A Endacott, and C Sutton, and L M Banks, and C Freemantle, and T J Spinks, and R Hesp
March 1988, Nutrition reviews,
J C Stevenson, and M I Whitehead, and M Padwick, and J A Endacott, and C Sutton, and L M Banks, and C Freemantle, and T J Spinks, and R Hesp
October 1984, British medical journal (Clinical research ed.),
Copied contents to your clipboard!