-transparent.png){kind=logo}
Human erythrocyte membranes metabolize inositol 1,3,4,5-tetrakisphosphate [Ins(1,3,4,5)P4] to inositol 1,3,4-trisphosphate [Ins(1,3,4)P3] in the presence of Mg2+. In the absence of Mg2+ a less rapid conversion of Ins(1,3,4,5)P4 into Ins(1,4,5)P3 was revealed. Such an enzyme activity, if present in hormonally sensitive cells, could provide a mechanism for maintaining constant concentrations of Ins(1,4,5)P3 and Ins(1,3,4,5)P4, important for stimulation of Ca2+ entry after Ca2+ mobilization.
Related Publications
C Doughney, and
M A McPherson, and
R L Dormer
October 1994,
Cell calcium,
C Doughney, and
M A McPherson, and
R L Dormer
February 1998,
The Journal of biological chemistry,
C Doughney, and
M A McPherson, and
R L Dormer
October 2005,
Biochemical and biophysical research communications,
C Doughney, and
M A McPherson, and
R L Dormer
August 1993,
British journal of pharmacology,
C Doughney, and
M A McPherson, and
R L Dormer
February 1989,
Biochemical Society transactions,
C Doughney, and
M A McPherson, and
R L Dormer
June 1994,
European journal of biochemistry,
C Doughney, and
M A McPherson, and
R L Dormer
September 1996,
FEBS letters,
C Doughney, and
M A McPherson, and
R L Dormer
April 1991,
Biochemical Society transactions,
C Doughney, and
M A McPherson, and
R L Dormer
July 1987,
FEBS letters,
C Doughney, and
M A McPherson, and
R L Dormer
March 1991,
Endocrinology,
