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Hemorrhagic necrotizing enterocolitis associated with Clostridium difficile infection in four foals. 1988
Diagnostic Laboratories, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins 80523.
Severe hemorrhagic necrotizing enterocolitis was determined to be the cause of death for 4 foals. Toxigenic Clostridium difficile was isolated form the intestine of each foal, and large, gram-positive, rod-shaped bacteria lined the surface of necrotic villi. This finding of toxigenic C difficile associated with enteritis in foals adds another possible cause to the list of infectious agents that should be considered when evaluating foals with enteritis. Definitive diagnosis requires a thorough diagnostic evaluation, including procedures that will identify the organism and demonstrate its toxigenicity.
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