BIOMAT Database Logo BIOMAT Database Logo

Characterization of a rare bla VIM-4 metallo-β-lactamase-producing Serratia marcescens clinical isolate in Hungary. 2020

Ákos Tóth, and Attila Makai, and Laura Jánvári, and Ivelina Damjanova, and Márió Gajdács, and Edit Urbán
Department of Bacteriology, Mycology and Parasitology, National Institute of Public Health, 1097, Albert Flórián út 2-6, Budapest, Hungary.

A carbapenem-resistant S. marcescens isolate was recovered from a patient with an inflammed pacemaker inplantation pocket from a Cardiac Surgery ward in a Hungarian University Hospital. Phenotypic tests and polymerase chain reaction (PCR) confirmed a very rare gene responsible for production of a carbapenemase ( ), which was further characterized by Sanger-sequencing. The characterization of this S. marcescens strain emphasizes the ongoing emergence of novel or rare carbapenemases. Strains expressing a weak carbapenemase like this strain might go unrecognized by routine diagnostics due to low minimum inhibitory concentrations (MICs) for the bacterial strains producing such enzymes.

UI MeSH Term Description Entries

Related Publications

Ákos Tóth, and Attila Makai, and Laura Jánvári, and Ivelina Damjanova, and Márió Gajdács, and Edit Urbán
Emergence of metallo-β-lactamase GIM-1 in a clinical isolate of Serratia marcescens.
September 2012, Antimicrobial agents and chemotherapy,
Ákos Tóth, and Attila Makai, and Laura Jánvári, and Ivelina Damjanova, and Márió Gajdács, and Edit Urbán
A new integron carrying VIM-2 metallo-beta-lactamase gene cassette in a Serratia marcescens isolate.
March 2002, Diagnostic microbiology and infectious disease,
Ákos Tóth, and Attila Makai, and Laura Jánvári, and Ivelina Damjanova, and Márió Gajdács, and Edit Urbán
Novel variant (bla(VIM-11)) of the metallo-{beta}-lactamase bla(VIM) family in a GES-1 extended-spectrum-{beta}-lactamase-producing Pseudomonas aeruginosa clinical isolate in Argentina.
January 2005, Antimicrobial agents and chemotherapy,
Ákos Tóth, and Attila Makai, and Laura Jánvári, and Ivelina Damjanova, and Márió Gajdács, and Edit Urbán
Isolation of a VIM-1 metallo-β-lactamase-producing Klebsiella pneumoniae isolate in Denmark.
November 2010, International journal of antimicrobial agents,
Ákos Tóth, and Attila Makai, and Laura Jánvári, and Ivelina Damjanova, and Márió Gajdács, and Edit Urbán
Escherichia coli ST471 Producing VIM-4 Metallo-β-Lactamase in Colombia.
March 2022, Microbial drug resistance (Larchmont, N.Y.),
Ákos Tóth, and Attila Makai, and Laura Jánvári, and Ivelina Damjanova, and Márió Gajdács, and Edit Urbán
Emergence of VIM-4 metallo-β-lactamase-producing Klebsiella pneumoniae ST15 clone in the Clinical Centre University of Pécs, Hungary.
January 2014, Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases,
Ákos Tóth, and Attila Makai, and Laura Jánvári, and Ivelina Damjanova, and Márió Gajdács, and Edit Urbán
First detection of a metallo-β-lactamase producing Serratia marcescens in a European university hospital.
January 2014, Indian journal of medical microbiology,
Ákos Tóth, and Attila Makai, and Laura Jánvári, and Ivelina Damjanova, and Márió Gajdács, and Edit Urbán
Molecular epidemiology of VIM-4 metallo-beta-lactamase-producing Pseudomonas sp. isolates in Hungary.
December 2006, Antimicrobial agents and chemotherapy,
Ákos Tóth, and Attila Makai, and Laura Jánvári, and Ivelina Damjanova, and Márió Gajdács, and Edit Urbán
Novel variant (bla(VIM-4)) of the metallo-beta-lactamase gene bla(VIM-1) in a clinical strain of Pseudomonas aeruginosa.
December 2002, Antimicrobial agents and chemotherapy,
Ákos Tóth, and Attila Makai, and Laura Jánvári, and Ivelina Damjanova, and Márió Gajdács, and Edit Urbán
First detection of VIM-4 metallo-β-lactamase-producing Escherichia coli in Russia.
July 2012, Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases,
Copied contents to your clipboard!