The potential of random pattern based computational ghost imaging (CGI) for real-time applications has been offset by its long image reconstruction time and inefficient reconstruction of complex diverse scenes. To overcome these problems, we propose a fast image reconstruction framework for CGI, called "DeepGhost", using deep convolutional autoencoder network to achieve real-time imaging at very low sampling rates (10-20%). By transferring prior-knowledge from STL-10 dataset to physical-data driven network, the proposed framework can reconstruct complex unseen targets with high accuracy. The experimental results show that the proposed method outperforms existing deep learning and state-of-the-art compressed sensing methods used for ghost imaging under similar conditions. The proposed method employs deep architecture with fast computation, and tackles the shortcomings of existing schemes i.e., inappropriate architecture, training on limited data under controlled settings, and employing shallow network for fast computation.