Biomaterial Database

Plasmonics meets super-resolution microscopy in biology. 2020

Miaoyan Wang, and Meiqi Li, and Shan Jiang, and Juntao Gao, and Peng Xi

Department of Biomedical Engineering, College of Engineering, Peking University, 100871 Beijing, China.

Super-resolution microscopy can reveal the subtle biological processes hidden behind the optical diffraction barrier. Plasmonics is a key nanophotonic that combines electronics and photonics through the interaction of light with the metallic nanostructure. In this review, we survey the recent progresses on plasmonic-assisted super-resolution microscopy. The strong electromagnetic field enhancement trapped near metallic nanostructures offers a unique opportunity to manipulate the illumination scheme for overcoming the diffraction limit. Plasmonic nanoprobes, exploited as surface-enhanced Raman scattering (SERS) and plasmon-enhanced fluorescence nanoparticles, are a major category of contrast agent in super-resolution microscopy. The outstanding challenges, future developments, and potential biological applications are also discussed.

UI	MeSH Term	Description	Entries
D008853	Microscopy	The use of instrumentation and techniques for visualizing material and details that cannot be seen by the unaided eye. It is usually done by enlarging images, transmitted by light or electron beams, with optical or magnetic lenses that magnify the entire image field. With scanning microscopy, images are generated by collecting output from the specimen in a point-by-point fashion, on a magnified scale, as it is scanned by a narrow beam of light or electrons, a laser, a conductive probe, or a topographical probe.	Compound Microscopy,Hand-Held Microscopy,Light Microscopy,Optical Microscopy,Simple Microscopy,Hand Held Microscopy,Microscopy, Compound,Microscopy, Hand-Held,Microscopy, Light,Microscopy, Optical,Microscopy, Simple
D004581	Electronics	The study, control, and application of the conduction of ELECTRICITY through gases or vacuum, or through semiconducting or conducting materials. (McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)	Electronic
D005453	Fluorescence	The property of emitting radiation while being irradiated. The radiation emitted is usually of longer wavelength than that incident or absorbed, e.g., a substance can be irradiated with invisible radiation and emit visible light. X-ray fluorescence is used in diagnosis.
D001695	Biology	One of the BIOLOGICAL SCIENCE DISCIPLINES concerned with the origin, structure, development, growth, function, genetics, and reproduction of animals, plants, and microorganisms.
D049329	Nanostructures	Materials which have structured components with at least one dimension in the range of 1 to 100 nanometers. These include NANOCOMPOSITES; NANOPARTICLES; NANOTUBES; and NANOWIRES.	Nanomaterials,Nanostructured Materials,Material, Nanostructured,Materials, Nanostructured,Nanomaterial,Nanostructure,Nanostructured Material
D053768	Metal Nanoparticles	Nanoparticles produced from metals whose uses include biosensors, optics, and catalysts. In biomedical applications the particles frequently involve the noble metals, especially gold and silver.	Metal Nanocrystals,Metallic Nanocrystals,Metallic Nanoparticles,Metal Nanocrystal,Metal Nanoparticle,Metallic Nanocrystal,Metallic Nanoparticle,Nanocrystal, Metal,Nanocrystal, Metallic,Nanocrystals, Metal,Nanocrystals, Metallic,Nanoparticle, Metal,Nanoparticle, Metallic,Nanoparticles, Metal,Nanoparticles, Metallic
D055095	Optics and Photonics	A specialized field of physics and engineering involved in studying the behavior and properties of light and the technology of analyzing, generating, transmitting, and manipulating ELECTROMAGNETIC RADIATION in the visible, infrared, and ultraviolet range.	Photonics,Photonics and Optics