Biomaterial Database

A DNA-intercalating compound derived from 7H-pyridocarbazole: the structure of 10-methoxy-2-methyl-7H-pyrido[4,3-c]carbazolium iodide. 1988

C Courseille, and D Pelaprat, and C C Tsai

Laboratoire de Cristallographie, UA 144 CNRS, Université de Bordeaux I, Talence, France.

C17H15N2O+.I-, Mr = 390.22, monoclinic, P21/c, a = 10.017 (2), b = 8.123 (5), c = 19.074 (4) A, beta = 95.86 (2) degrees, V = 1544 (2) A3, Z = 4, D chi = 1.67 g cm-3, mu = 2.10 cm-1, lambda (Mo K alpha) = 0.7107 A, F(000) = 768, R = 0.04 for 1236 unique reflections measured at 295 K. Dimensions of the ring system are similar to those found in 6H-pyridocarbazole analogues (ellipticine derivatives). The iodine ion and pyridocarbazolium system are linked by a hydrogen bond. The planar 7H-pyridocarbazole cations form stacks approximately parallel to b. Interactions between stacks occur by weak van der Waals forces.

UI	MeSH Term	Description	Entries
D007364	Intercalating Agents	Agents that are capable of inserting themselves between the successive bases in DNA, thus kinking, uncoiling or otherwise deforming it and therefore preventing its proper functioning. They are used in the study of DNA.	Intercalating Agent,Intercalating Ligand,Intercalative Compound,Intercalator,Intercalators,Intercalating Ligands,Intercalative Compounds,Agent, Intercalating,Agents, Intercalating,Compound, Intercalative,Compounds, Intercalative,Ligand, Intercalating,Ligands, Intercalating
D008958	Models, Molecular	Models used experimentally or theoretically to study molecular shape, electronic properties, or interactions; includes analogous molecules, computer-generated graphics, and mechanical structures.	Molecular Models,Model, Molecular,Molecular Model
D002227	Carbazoles	Benzo-indoles similar to CARBOLINES which are pyrido-indoles. In plants, carbazoles are derived from indole and form some of the INDOLE ALKALOIDS.
D014961	X-Ray Diffraction	The scattering of x-rays by matter, especially crystals, with accompanying variation in intensity due to interference effects. Analysis of the crystal structure of materials is performed by passing x-rays through them and registering the diffraction image of the rays (CRYSTALLOGRAPHY, X-RAY). (From McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)	Xray Diffraction,Diffraction, X-Ray,Diffraction, Xray,Diffractions, X-Ray,Diffractions, Xray,X Ray Diffraction,X-Ray Diffractions,Xray Diffractions
D015394	Molecular Structure	The location of the atoms, groups or ions relative to one another in a molecule, as well as the number, type and location of covalent bonds.	Structure, Molecular,Molecular Structures,Structures, Molecular