Biomaterial Database

Oxybutynin chloride combined with intermittent clean catheterization in the treatment of myelomeningocele patients. 1977

J J Mulcahy, and H E James, and J W McRoberts

Oxybutynin chloride has been with intermittent clean catheterization to achieve urinary continence in 21 of 25 myelomeningocele patients (84 per cent success rate). The regimen, results, problems and implications of this new method of treatment are discussed.

UI	MeSH Term	Description	Entries
D008333	Mandelic Acids	Analogs or derivatives of mandelic acid (alpha-hydroxybenzeneacetic acid).	Acids, Mandelic
D008591	Meningomyelocele	Congenital, or rarely acquired, herniation of meningeal and spinal cord tissue through a bony defect in the vertebral column. The majority of these defects occur in the lumbosacral region. Clinical features include PARAPLEGIA, loss of sensation in the lower body, and incontinence. This condition may be associated with the ARNOLD-CHIARI MALFORMATION and HYDROCEPHALUS. (From Joynt, Clinical Neurology, 1992, Ch55, pp35-6)	Myelocele,Myelomeningocele,Acquired Meningomyelocele,Myelomeningocele, Acquired,Acquired Meningomyeloceles,Acquired Myelomeningocele,Acquired Myelomeningoceles,Meningomyelocele, Acquired,Meningomyeloceles,Meningomyeloceles, Acquired,Myeloceles,Myelomeningoceles,Myelomeningoceles, Acquired
D002648	Child	A person 6 to 12 years of age. An individual 2 to 5 years old is CHILD, PRESCHOOL.	Children
D002675	Child, Preschool	A child between the ages of 2 and 5.	Children, Preschool,Preschool Child,Preschool Children
D003510	Cyclohexanes	Six-carbon alicyclic hydrocarbons.
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D014546	Urinary Catheterization	Passage of a CATHETER into the URINARY BLADDER or kidney.	Catheterization, Ureteral,Catheterization, Urethral,Catheterization, Urinary,Foley Catheterization,Ureteral Catheterization,Urethral Catheterization,Catheterization, Foley,Catheterizations, Ureteral,Catheterizations, Urethral,Catheterizations, Urinary,Ureteral Catheterizations,Urethral Catheterizations,Urinary Catheterizations
D014549	Urinary Incontinence	Involuntary loss of URINE, such as leaking of urine. It is a symptom of various underlying pathological processes. Major types of incontinence include URINARY URGE INCONTINENCE and URINARY STRESS INCONTINENCE.	Incontinence, Urinary
D016135	Spinal Dysraphism	Congenital defects of closure of one or more vertebral arches, which may be associated with malformations of the spinal cord, nerve roots, congenital fibrous bands, lipomas, and congenital cysts. These malformations range from mild (e.g., SPINA BIFIDA OCCULTA) to severe, including rachischisis where there is complete failure of neural tube and spinal cord fusion, resulting in exposure of the spinal cord at the surface. Spinal dysraphism includes all forms of spina bifida. The open form is called SPINA BIFIDA CYSTICA and the closed form is SPINA BIFIDA OCCULTA. (From Joynt, Clinical Neurology, 1992, Ch55, p34)	Rachischisis,Spina Bifida,Status Dysraphicus,Cleft Spine,Open Spine,Schistorrhachis,Spinal Dysraphia,Bifida, Spina,Cleft Spines,Dysraphia, Spinal,Dysraphicus, Status,Dysraphism, Spinal,Dysraphisms, Spinal,Open Spines,Rachischises,Spina Bifidas,Spinal Dysraphias,Spinal Dysraphisms,Spine, Cleft,Spine, Open