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Smoke inhalation causes most of the deaths in fire-related injuries, with pulmonary edema as a major determinant in the outcome of smoke-inhalation injury. The pathophysiology of pulmonary edema is thought to be related to the products of incomplete combustion. Damage to the integrity of the alveolar epithelium is one of the determinants of the development of smoke-induced pulmonary edema. In recent studies using lung clearance of aerosolized pentetic acid (DTPA [diethylenetriaminepentaacetic acid]) labeled with technetium Tc 99m to assess the permeability of the alveolar epithelium, several factors were identified that may increase a person's susceptibility to smoke-induced acute lung injury. These are increased initial alveolar permeability and alterations in the number and activity of alveolar macrophages. Clinical measurement of (99m)TcDTPA clearance may provide a sensitive and convenient method for the early detection and serial assessment of smoke-induced alveolar epithelial permeability changes.
M L Witten, and
S F Quan, and
R E Sobonya, and
R J Lemen
January 1985,
The Journal of burn care & rehabilitation,
M L Witten, and
S F Quan, and
R E Sobonya, and
R J Lemen
January 1975,
Surgical forum,
M L Witten, and
S F Quan, and
R E Sobonya, and
R J Lemen
September 1987,
Journal of applied physiology (Bethesda, Md. : 1985),
M L Witten, and
S F Quan, and
R E Sobonya, and
R J Lemen
January 2018,
Acute medicine,
M L Witten, and
S F Quan, and
R E Sobonya, and
R J Lemen
January 1995,
Journal of applied physiology (Bethesda, Md. : 1985),
M L Witten, and
S F Quan, and
R E Sobonya, and
R J Lemen
December 1986,
The American review of respiratory disease,
M L Witten, and
S F Quan, and
R E Sobonya, and
R J Lemen
June 1971,
Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete,
M L Witten, and
S F Quan, and
R E Sobonya, and
R J Lemen
January 1965,
Journal de physiologie,
M L Witten, and
S F Quan, and
R E Sobonya, and
R J Lemen
November 1998,
Ugeskrift for laeger,
M L Witten, and
S F Quan, and
R E Sobonya, and
R J Lemen
July 1982,
Journal of the National Cancer Institute,
