Eighty consecutive cases of gamete intra-fallopian transfer. 1988

P C Wong, and S C Ng, and M P Hamilton, and C Anandakumar, and Y C Wong, and S S Ratnam
Department of Obstetrics and Gynaecology, National University Hospital, Republic of Singapore.

Eighty patients with the main problems of unexplained infertility, oligospermia and endometriosis were treated with gamete intra-Fallopian transfer (GIFT). From 80 treatment cycles, 29 women conceived (36.3%). Of these, four were biochemical pregnancies and therefore the clinical pregnancy rate (25/80) was 31.2%. There were six sets of multiple pregnancies, a multiple pregnancy rate of 24%. Three women (12%) miscarried. The pregnancy rates in the patients with unexplained infertility, oligospermia and endometriosis were 33.3, 16.7 and 38.5%, respectively. The transfer of four oocytes appears to increase the pregnancy rate without increasing the risk of multiple pregnancy. The presence of in-vitro fertilization of excess oocytes after GIFT did not correlate with the final outcome of GIFT.

UI MeSH Term Description Entries
D011247 Pregnancy The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH. Gestation,Pregnancies
D012099 Reproductive Techniques Methods pertaining to the generation of new individuals, including techniques used in selective BREEDING, cloning (CLONING, ORGANISM), and assisted reproduction (REPRODUCTIVE TECHNIQUES, ASSISTED). Reproductive Technology,Reproduction Technics,Reproduction Techniques,Reproductive Technologies,Technology, Reproductive,Reproduction Technic,Reproduction Technique,Reproductive Technique,Technic, Reproduction,Technics, Reproduction,Technique, Reproduction,Technique, Reproductive,Techniques, Reproduction,Techniques, Reproductive,Technologies, Reproductive
D005187 Fallopian Tubes A pair of highly specialized canals extending from the UTERUS to its corresponding OVARY. They provide the means for OVUM transport from the ovaries and they are the site of the ovum's final maturation and FERTILIZATION. The fallopian tube consists of an interstitium, an isthmus, an ampulla, an infundibulum, and fimbriae. Its wall consists of three layers: serous, muscular, and an internal mucosal layer lined with both ciliated and secretory cells. Oviducts, Mammalian,Salpinges, Uterine,Salpinx, Uterine,Uterine Salpinges,Uterine Salpinx,Fallopian Tube,Uterine Tubes,Mammalian Oviduct,Mammalian Oviducts,Oviduct, Mammalian,Tube, Fallopian,Tube, Uterine,Tubes, Fallopian,Tubes, Uterine,Uterine Tube
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man

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