Alpha-lipoic acid improves the reproduction performance of breeder hens during the late egg-laying period. 2020

Hongjian Dai, and Zengpeng Lv, and Chenhui Hu, and Zhicheng Shi, and Xihui Wei, and Song Jin, and Yunwei Yuan, and Debing Yu, and Fangxiong Shi
College of Animal Science and Technology, Nanjing Agricultural University, Nanjing, China.

Alpha-lipoic acid (ALA), a multifunctional antioxidant, can promote fatty acid mobilization, energy expenditure and scavenge free radicals. The effects of dietary ALA on the reproductive performance of breeder hens were investigated in the current study. In the 5-week experiment, 180 54-week-old Qiling breeder hens were randomly divided into three treatments with five replicates and supplemented with three levels of ALA (0, 300 and 600 mg/kg) in the basic corn-soya bean meal diets. 600 mg/kg ALA treatment group (HLA) significantly improved the eggshell thickness and strength (p < .05). ALA-treated groups improved egg-laying rate compared with the CON group, but with no statistically significant difference (p > .05). The levels of HDL-C, ALB and estradiol (E2) of the serum in the HLA group were elevated compared with the CON group (p < .05). In addition, ALA (600 mg/kg) treatment exhibited a reduced level of serum AST and TG (p < .05). Dietary ALA increased the activity of hepatic lipase in liver (p < .05). Supplemental 600 mg/kg ALA also improved the SOD activity and total antioxidant capacity level, along with a decreased MDA in ovarian tissue (p < .05). Furthermore, the mRNA expressions of ESR1, ESR2, VTG2 and ApoB in the liver and FSHR in follicles were upregulated in the HLA group (p < .05). In conclusion, dietary supplementation with 600 mg/kg ALA during the late egg-laying period could improve lipid metabolism and reproductive performance of breeder hens.

UI MeSH Term Description Entries
D008063 Thioctic Acid An octanoic acid bridged with two sulfurs so that it is sometimes also called a pentanoic acid in some naming schemes. It is biosynthesized by cleavage of LINOLEIC ACID and is a coenzyme of oxoglutarate dehydrogenase (KETOGLUTARATE DEHYDROGENASE COMPLEX). It is used in DIETARY SUPPLEMENTS. Lipoic Acid,Alpha-Lipogamma,Alpha-Lipon Stada,Alpha-Liponsaure Sofotec,Alpha-Lippon AL,Alphaflam,Azulipont,Fenint,Juthiac,Liponsaure-ratiopharm,MTW-Alphaliponsaure,Neurium,Pleomix-Alpha,Pleomix-Alpha N,Thioctacid,Thioctacide T,Thiogamma Injekt,Thiogamma oral,Tromlipon,Verla-Lipon,alpha-Lipoic Acid,alpha-Liponaure Heumann,alpha-Liponsaure von ct,alpha-Vibolex,biomo-lipon,duralipon,espa-lipon,Acid, alpha-Lipoic,Alpha Lipogamma,Alpha Lipon Stada,Alpha Liponsaure Sofotec,Alpha Lippon AL,AlphaLipogamma,AlphaLipon Stada,AlphaLiponsaure Sofotec,AlphaLippon AL,Injekt, Thiogamma,Liponsaure ratiopharm,Liponsaureratiopharm,MTW Alphaliponsaure,MTWAlphaliponsaure,Pleomix Alpha,Pleomix Alpha N,PleomixAlpha,PleomixAlpha N,Verla Lipon,VerlaLipon,alpha Lipoic Acid,alpha Liponaure Heumann,alpha Liponsaure von ct,alpha Vibolex,alphaLiponaure Heumann,alphaLiponsaure von ct,alphaVibolex,biomo lipon,biomolipon,espa lipon,espalipon
D010063 Ovum A mature haploid female germ cell extruded from the OVARY at OVULATION. Egg,Egg, Unfertilized,Ova,Eggs, Unfertilized,Unfertilized Egg,Unfertilized Eggs
D012098 Reproduction The total process by which organisms produce offspring. (Stedman, 25th ed) Human Reproductive Index,Human Reproductive Indexes,Reproductive Period,Human Reproductive Indices,Index, Human Reproductive,Indexes, Human Reproductive,Indices, Human Reproductive,Period, Reproductive,Periods, Reproductive,Reproductive Index, Human,Reproductive Indices, Human,Reproductive Periods
D002645 Chickens Common name for the species Gallus gallus, the domestic fowl, in the family Phasianidae, order GALLIFORMES. It is descended from the red jungle fowl of SOUTHEAST ASIA. Gallus gallus,Gallus domesticus,Gallus gallus domesticus,Chicken
D004032 Diet Regular course of eating and drinking adopted by a person or animal. Diets
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D000821 Animal Feed Foodstuff used especially for domestic and laboratory animals, or livestock. Fodder,Animal Feeds,Feed, Animal,Feeds, Animal,Fodders
D019587 Dietary Supplements Products in capsule, tablet or liquid form that provide dietary ingredients, and that are intended to be taken by mouth to increase the intake of nutrients. Dietary supplements can include macronutrients, such as proteins, carbohydrates, and fats; and/or MICRONUTRIENTS, such as VITAMINS; MINERALS; and PHYTOCHEMICALS. Food Supplements,Neutraceuticals,Dietary Supplementations,Food Supplementations,Herbal Supplements,Nutraceuticals,Nutriceuticals,Dietary Supplement,Food Supplement,Herbal Supplement,Neutraceutical,Nutraceutical,Nutriceutical,Supplement, Food,Supplement, Herbal,Supplementations, Dietary,Supplements, Dietary,Supplements, Food,Supplements, Herbal

Related Publications

Hongjian Dai, and Zengpeng Lv, and Chenhui Hu, and Zhicheng Shi, and Xihui Wei, and Song Jin, and Yunwei Yuan, and Debing Yu, and Fangxiong Shi
December 2019, Poultry science,
Hongjian Dai, and Zengpeng Lv, and Chenhui Hu, and Zhicheng Shi, and Xihui Wei, and Song Jin, and Yunwei Yuan, and Debing Yu, and Fangxiong Shi
September 2022, Poultry science,
Hongjian Dai, and Zengpeng Lv, and Chenhui Hu, and Zhicheng Shi, and Xihui Wei, and Song Jin, and Yunwei Yuan, and Debing Yu, and Fangxiong Shi
January 2013, British poultry science,
Hongjian Dai, and Zengpeng Lv, and Chenhui Hu, and Zhicheng Shi, and Xihui Wei, and Song Jin, and Yunwei Yuan, and Debing Yu, and Fangxiong Shi
August 2020, Poultry science,
Hongjian Dai, and Zengpeng Lv, and Chenhui Hu, and Zhicheng Shi, and Xihui Wei, and Song Jin, and Yunwei Yuan, and Debing Yu, and Fangxiong Shi
November 2022, Animal bioscience,
Hongjian Dai, and Zengpeng Lv, and Chenhui Hu, and Zhicheng Shi, and Xihui Wei, and Song Jin, and Yunwei Yuan, and Debing Yu, and Fangxiong Shi
February 2022, Poultry science,
Hongjian Dai, and Zengpeng Lv, and Chenhui Hu, and Zhicheng Shi, and Xihui Wei, and Song Jin, and Yunwei Yuan, and Debing Yu, and Fangxiong Shi
May 2023, Poultry science,
Hongjian Dai, and Zengpeng Lv, and Chenhui Hu, and Zhicheng Shi, and Xihui Wei, and Song Jin, and Yunwei Yuan, and Debing Yu, and Fangxiong Shi
December 2015, Poultry science,
Hongjian Dai, and Zengpeng Lv, and Chenhui Hu, and Zhicheng Shi, and Xihui Wei, and Song Jin, and Yunwei Yuan, and Debing Yu, and Fangxiong Shi
July 2020, Journal of animal science and technology,
Hongjian Dai, and Zengpeng Lv, and Chenhui Hu, and Zhicheng Shi, and Xihui Wei, and Song Jin, and Yunwei Yuan, and Debing Yu, and Fangxiong Shi
January 2022, Journal of animal science and biotechnology,
Copied contents to your clipboard!