Biomaterial Database

Effect of fluoride on autogenous iliac cancellous bone and marrow transplants in surgically created intrabony pockets in dogs. 1977

A Stabholz, and L Brayer, and I Gedalia, and Z Yosipovitch, and W A Soskolne

The effect of the osteogenic capacity of fluoride on autogenous iliac cancellous bone and marrow transplants was studied in experimentally created periodontal defects. Eight dogs, 2 years old, weighing between 10 to 15 kg each, were used. The right side of the upper jaw served for creation of the experimental (fluoride-treated) pockets and the left side for the control (saline-treated) pockets. Fluoride treatment was carried out by a single topical application of a high concentration of fluoride in the periodontal defects and by application of a low concentration of fluoride to the bone marrow transplants. Intraoral periapical radiographs were taken immediately after implantation, and at time of sacrifice. Changes during bone healing were assessed histologically and by radioopacity measurements. The newly formed bone in the control and fluoride-treated areas did not differ in quality. Radioopacity in the experimental defects was significantly higher in comparison with that found in the control areas. The increase was probably due to greater bone formation in the fluoride-treated defects. The difference decreased with the duration of the healing intervals. Cementum was deposited in both control and experimental sites.

UI	MeSH Term	Description	Entries
D007085	Ilium	The largest of three bones that make up each half of the pelvic girdle.	Auricular Surface of Ilium,Iliac Crest,Iliac Crest Bone,Iliac Fossa,Bones, Iliac Crest,Crest Bone, Iliac,Crest Bones, Iliac,Crest, Iliac,Crests, Iliac,Fossa, Iliac,Iliac Crest Bones,Iliac Crests,Iliums
D010012	Osteogenesis	The process of bone formation. Histogenesis of bone including ossification.	Bone Formation,Ossification, Physiologic,Endochondral Ossification,Ossification,Ossification, Physiological,Osteoclastogenesis,Physiologic Ossification,Endochondral Ossifications,Ossification, Endochondral,Ossifications,Ossifications, Endochondral,Osteoclastogeneses,Physiological Ossification
D010518	Periodontitis	Inflammation and loss of connective tissues supporting or surrounding the teeth. This may involve any part of the PERIODONTIUM. Periodontitis is currently classified by disease progression (CHRONIC PERIODONTITIS; AGGRESSIVE PERIODONTITIS) instead of age of onset. (From 1999 International Workshop for a Classification of Periodontal Diseases and Conditions, American Academy of Periodontology)	Pericementitis,Pericementitides,Periodontitides
D011859	Radiography	Examination of any part of the body for diagnostic purposes by means of X-RAYS or GAMMA RAYS, recording the image on a sensitized surface (such as photographic film).	Radiology, Diagnostic X-Ray,Roentgenography,X-Ray, Diagnostic,Diagnostic X-Ray,Diagnostic X-Ray Radiology,X-Ray Radiology, Diagnostic,Diagnostic X Ray,Diagnostic X Ray Radiology,Diagnostic X-Rays,Radiology, Diagnostic X Ray,X Ray Radiology, Diagnostic,X Ray, Diagnostic,X-Rays, Diagnostic
D001854	Bone Marrow Cells	Cells contained in the bone marrow including fat cells (see ADIPOCYTES); STROMAL CELLS; MEGAKARYOCYTES; and the immediate precursors of most blood cells.	Bone Marrow Cell,Cell, Bone Marrow,Cells, Bone Marrow,Marrow Cell, Bone,Marrow Cells, Bone
D004285	Dogs	The domestic dog, Canis familiaris, comprising about 400 breeds, of the carnivore family CANIDAE. They are worldwide in distribution and live in association with people. (Walker's Mammals of the World, 5th ed, p1065)	Canis familiaris,Dog
D005459	Fluorides	Inorganic salts of hydrofluoric acid, HF, in which the fluorine atom is in the -1 oxidation state. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed) Sodium and stannous salts are commonly used in dentifrices.	Fluoride
D005888	Gingival Pocket	An abnormal extension of a gingival sulcus not accompanied by the apical migration of the epithelial attachment.	Pocket, Gingival,Gingival Pockets,Pockets, Gingival
D000539	Alveolar Process	The thickest and spongiest part of the maxilla and mandible hollowed out into deep cavities for the teeth.	Alveolar Ridge,Alveolar Processes,Process, Alveolar,Processes, Alveolar,Ridge, Alveolar
D000543	Alveoloplasty	Conservative contouring of the alveolar process, in preparation for immediate or future denture construction. (Dorland, 28th ed)	Alveoloplasties