This paper is based on the author's experience and a review of the most recent literature. First, the five most common tumors are discussed: ganglia, giant cell tumor, mucous cyst, hemangioma, and epithelial inclusion cyst. The less-common lesions are then discussed that present special problems in the hand, such as the glomus tumor or recurring digital fibromatosis of childhood among others. Lastly, the general guidelines for treatment of malignant tumors of the soft tissue tumors of the hand are presented, followed by a description of a selection of lesions (epitheloid sarcoma, subungual malignant tumors, Kaposi's sarcoma).