[Value of the detection and characterization of circulating immune complexes in rheumatoid arthritis]. 1977

P Wattre, and B Delcambre, and F Santoro, and D Defrance, and H B Duquesnoy

The authors analyse the value of research into and identification of immune complexes (IC) in chronic inflammatory rheumatisms (CIR) and in rheumatoid polyarthritis (RP) in 93 patients hospitalise in a Rheumatology Department. Comparative levels of ICs were established simple and quick technique of measuring the 50% haemolytic complement (HC 50) used up by the ICs. The rheumatoid factor (RF) is identified at the PEG IC precipitates with the Waaler-Rose test. The existence of raised levels of IC containing RF in both seropositive and seronegative PRs and to a similar degree in a non-negligable percentage of clinically non-classable RICs conforms the diagnostic value of this research. On the other hand there is no relationship between the levels of ICs and either clinical signs or age of the illness. In RPs other than CIR circulating ICs are found whose nature is still unknown.

UI MeSH Term Description Entries
D007457 Iodine Radioisotopes Unstable isotopes of iodine that decay or disintegrate emitting radiation. I atoms with atomic weights 117-139, except I 127, are radioactive iodine isotopes. Radioisotopes, Iodine
D011092 Polyethylene Glycols Polymers of ETHYLENE OXIDE and water, and their ethers. They vary in consistency from liquid to solid depending on the molecular weight indicated by a number following the name. They are used as SURFACTANTS, dispersing agents, solvents, ointment and suppository bases, vehicles, and tablet excipients. Some specific groups are NONOXYNOLS, OCTOXYNOLS, and POLOXAMERS. Macrogols,Polyoxyethylenes,Carbowax,Macrogol,Polyethylene Glycol,Polyethylene Oxide,Polyethyleneoxide,Polyglycol,Glycol, Polyethylene,Glycols, Polyethylene,Oxide, Polyethylene,Oxides, Polyethylene,Polyethylene Oxides,Polyethyleneoxides,Polyglycols,Polyoxyethylene
D002986 Clinical Trials as Topic Works about pre-planned studies of the safety, efficacy, or optimum dosage schedule (if appropriate) of one or more diagnostic, therapeutic, or prophylactic drugs, devices, or techniques selected according to predetermined criteria of eligibility and observed for predefined evidence of favorable and unfavorable effects. This concept includes clinical trials conducted both in the U.S. and in other countries. Clinical Trial as Topic
D003168 Complement Fixation Tests Serologic tests based on inactivation of complement by the antigen-antibody complex (stage 1). Binding of free complement can be visualized by addition of a second antigen-antibody system such as red cells and appropriate red cell antibody (hemolysin) requiring complement for its completion (stage 2). Failure of the red cells to lyse indicates that a specific antigen-antibody reaction has taken place in stage 1. If red cells lyse, free complement is present indicating no antigen-antibody reaction occurred in stage 1. Complement Absorption Test, Conglutinating,Conglutination Reaction,Conglutinating Complement Absorption Test,Complement Fixation Test,Conglutination Reactions,Fixation Test, Complement,Fixation Tests, Complement,Reaction, Conglutination,Reactions, Conglutination,Test, Complement Fixation,Tests, Complement Fixation
D003172 Complement C1 The first complement component to act in the activation of CLASSICAL COMPLEMENT PATHWAY. It is a calcium-dependent trimolecular complex made up of three subcomponents: COMPLEMENT C1Q; COMPLEMENT C1R; and COMPLEMENT C1S at 1:2:2 ratios. When the intact C1 binds to at least two antibodies (involving C1q), C1r and C1s are sequentially activated, leading to subsequent steps in the cascade of COMPLEMENT ACTIVATION. C1 Complement,Complement 1,Complement Component 1,C1, Complement,Complement, C1,Component 1, Complement
D003937 Diagnosis, Differential Determination of which one of two or more diseases or conditions a patient is suffering from by systematically comparing and contrasting results of diagnostic measures. Diagnoses, Differential,Differential Diagnoses,Differential Diagnosis
D006386 Hemagglutination Tests Sensitive tests to measure certain antigens, antibodies, or viruses, using their ability to agglutinate certain erythrocytes. (From Stedman, 26th ed) Hemagglutination Test,Test, Hemagglutination,Tests, Hemagglutination
D006461 Hemolysis The destruction of ERYTHROCYTES by many different causal agents such as antibodies, bacteria, chemicals, temperature, and changes in tonicity. Haemolysis,Extravascular Hemolysis,Intravascular Hemolysis,Extravascular Hemolyses,Haemolyses,Hemolyses, Extravascular,Hemolyses, Intravascular,Hemolysis, Extravascular,Hemolysis, Intravascular,Intravascular Hemolyses
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000936 Antigen-Antibody Complex The complex formed by the binding of antigen and antibody molecules. The deposition of large antigen-antibody complexes leading to tissue damage causes IMMUNE COMPLEX DISEASES. Immune Complex,Antigen-Antibody Complexes,Immune Complexes,Antigen Antibody Complex,Antigen Antibody Complexes,Complex, Antigen-Antibody,Complex, Immune,Complexes, Antigen-Antibody,Complexes, Immune

Related Publications

P Wattre, and B Delcambre, and F Santoro, and D Defrance, and H B Duquesnoy
September 1976, Biomedicine / [publiee pour l'A.A.I.C.I.G.],
P Wattre, and B Delcambre, and F Santoro, and D Defrance, and H B Duquesnoy
October 1985, The Journal of rheumatology,
P Wattre, and B Delcambre, and F Santoro, and D Defrance, and H B Duquesnoy
January 1981, Voprosy revmatizma,
P Wattre, and B Delcambre, and F Santoro, and D Defrance, and H B Duquesnoy
June 1987, The Journal of rheumatology,
P Wattre, and B Delcambre, and F Santoro, and D Defrance, and H B Duquesnoy
November 1983, Bollettino dell'Istituto sieroterapico milanese,
P Wattre, and B Delcambre, and F Santoro, and D Defrance, and H B Duquesnoy
October 1983, Ryumachi. [Rheumatism],
P Wattre, and B Delcambre, and F Santoro, and D Defrance, and H B Duquesnoy
January 1984, Annales de biologie clinique,
P Wattre, and B Delcambre, and F Santoro, and D Defrance, and H B Duquesnoy
January 1990, Clinical and experimental rheumatology,
P Wattre, and B Delcambre, and F Santoro, and D Defrance, and H B Duquesnoy
January 1987, Pediatriia,
P Wattre, and B Delcambre, and F Santoro, and D Defrance, and H B Duquesnoy
January 1978, Rheumatology and rehabilitation,
Copied contents to your clipboard!