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Twelve normotensive patients with coronary artery disease and stable effort-induced angina pectoris were selected: the antiischemic effect of captopril was studied. A maximal cycloergometer effort test was obtained before (base) and after administration of placebo or captopril (50 mg p.o.). The following parameters were measured: heart rate (HR), blood pressure (BP), maximal rate/pressure product (MRPP), maximal workload sustained, (MWS), maximal working time (MWT), and S-T depression at MRPP. The base and placebo were similar. Compared to them captopril augmented the MWT, increased the MWS, reduced S-T depression at MRPP, and decreased the number of patients with effort-induced angina pectoris. The antiischemic effect of captopril seems related both to its effect on HR and BP, and to a local enhancement of coronary blood flow.
C Strozzi, and
G Cocco, and
F Portaluppi, and
L Urso, and
R Alfiero, and
M T Tasini, and
L Montanari, and
K Al Yassini, and
A Rizzo
September 2007,
Nihon rinsho. Japanese journal of clinical medicine,
C Strozzi, and
G Cocco, and
F Portaluppi, and
L Urso, and
R Alfiero, and
M T Tasini, and
L Montanari, and
K Al Yassini, and
A Rizzo
January 1992,
Archivos del Instituto de Cardiologia de Mexico,
C Strozzi, and
G Cocco, and
F Portaluppi, and
L Urso, and
R Alfiero, and
M T Tasini, and
L Montanari, and
K Al Yassini, and
A Rizzo
August 1959,
Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke,
C Strozzi, and
G Cocco, and
F Portaluppi, and
L Urso, and
R Alfiero, and
M T Tasini, and
L Montanari, and
K Al Yassini, and
A Rizzo
December 1989,
The Tokushima journal of experimental medicine,
C Strozzi, and
G Cocco, and
F Portaluppi, and
L Urso, and
R Alfiero, and
M T Tasini, and
L Montanari, and
K Al Yassini, and
A Rizzo
May 1982,
Kardiologiia,
C Strozzi, and
G Cocco, and
F Portaluppi, and
L Urso, and
R Alfiero, and
M T Tasini, and
L Montanari, and
K Al Yassini, and
A Rizzo
May 2003,
Nihon rinsho. Japanese journal of clinical medicine,
C Strozzi, and
G Cocco, and
F Portaluppi, and
L Urso, and
R Alfiero, and
M T Tasini, and
L Montanari, and
K Al Yassini, and
A Rizzo
May 1989,
Zhongguo yao li xue bao = Acta pharmacologica Sinica,
C Strozzi, and
G Cocco, and
F Portaluppi, and
L Urso, and
R Alfiero, and
M T Tasini, and
L Montanari, and
K Al Yassini, and
A Rizzo
August 1981,
Chest,
C Strozzi, and
G Cocco, and
F Portaluppi, and
L Urso, and
R Alfiero, and
M T Tasini, and
L Montanari, and
K Al Yassini, and
A Rizzo
March 1990,
Casopis lekaru ceskych,
C Strozzi, and
G Cocco, and
F Portaluppi, and
L Urso, and
R Alfiero, and
M T Tasini, and
L Montanari, and
K Al Yassini, and
A Rizzo
September 1962,
Folia medica Neerlandica,
