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Changes induced in the endocrine pancreas were studied in rats 14 days after ovariectomy. The study was performed in age matched control (C) and ovariectomized (O) rats. The pancreases were stained using the p-aldehyde-fuchsin and the peroxidase (using antiinsulin serum) methods. Morphometric analysis was done using the Weibel technique. The results obtained show a diminution in the total volume of the endocrine pancreas accompanied by an increment in the individual islet volume following the ovariectomy. The last change would be the consequence of an increment in the number of islet cells (mainly the B cell population), without change in cellular volume, i.e., hyperplasia without hypertrophy. These changes might explain the apparent discrepancy regarding the effect of ovariectomy upon insulin secretion when this process is studied using either the total pancreas preparation or the isolated islet model.
M C Semino, and
M E García, and
A M Galeano, and
C L Gómez Dumm, and
E E de Gagliardino, and
J J Gagliardino
January 1983,
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme,
M C Semino, and
M E García, and
A M Galeano, and
C L Gómez Dumm, and
E E de Gagliardino, and
J J Gagliardino
February 2008,
Calcified tissue international,
M C Semino, and
M E García, and
A M Galeano, and
C L Gómez Dumm, and
E E de Gagliardino, and
J J Gagliardino
January 1981,
Zeitschrift fur experimentelle Chirurgie,
M C Semino, and
M E García, and
A M Galeano, and
C L Gómez Dumm, and
E E de Gagliardino, and
J J Gagliardino
December 2011,
Archivum immunologiae et therapiae experimentalis,
M C Semino, and
M E García, and
A M Galeano, and
C L Gómez Dumm, and
E E de Gagliardino, and
J J Gagliardino
September 2016,
Diabetes, obesity & metabolism,
M C Semino, and
M E García, and
A M Galeano, and
C L Gómez Dumm, and
E E de Gagliardino, and
J J Gagliardino
January 2022,
BioMed research international,
M C Semino, and
M E García, and
A M Galeano, and
C L Gómez Dumm, and
E E de Gagliardino, and
J J Gagliardino
January 1989,
International archives of occupational and environmental health,
M C Semino, and
M E García, and
A M Galeano, and
C L Gómez Dumm, and
E E de Gagliardino, and
J J Gagliardino
December 2010,
Photosynthesis research,
M C Semino, and
M E García, and
A M Galeano, and
C L Gómez Dumm, and
E E de Gagliardino, and
J J Gagliardino
September 1998,
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research,
M C Semino, and
M E García, and
A M Galeano, and
C L Gómez Dumm, and
E E de Gagliardino, and
J J Gagliardino
October 2013,
Blood,
