Biomaterial Database

Prospective and comparative Novel technique for evaluation the affinity of alginate for binding the alkaline-earth metal ions during formation the coordination biopolymer hydrogel complexes. 2020

Refat M Hassan

Chemistry Department, Faculty of Science, Assiut University, Assiut 71516, Egypt. Electronic address: rmhassan2002@yahoo.com.

A prospective novel technique has been developed for evaluation the capacity of alginate as a natural polymer absorbent for binding Ca (II), Sr (II) and Ba(II) as alkaline earth metal ions for formation of coordination biopolymer hydrogel complexes. This method was based on avoiding the non-chelated metal-ions which may present free into the interstitial spaces of the spongy network of the alginate matrix. Neglecting of non-chelated metal ions in the various techniques will lead to miscalculation in the definite concentration of the binding metal ions. Hence, some uncertainty and dissimilarity were observed in the reported data with respect to the alginate capacity for binding the metal ions. Therefore, a novel technique for more precise determination was achieved by synthesis of coordination metal alginate gels of granule nature which are free from such non-chelated metal ions. Here, the true binding metal ions were eluted by addition of dilute HClO4 and the concentration of the metal ions into the effluent was determined, conductometrically. The experimental results indicated that the capacity of alginate was decreased in the order Ba2+ > Sr2+ > Ca2+ ions in good accord with their thermal stability. The factors affected the affinity of alginate for binding the metal ions were interpreted and discussed.

UI	MeSH Term	Description	Entries
D007477	Ions	An atom or group of atoms that have a positive or negative electric charge due to a gain (negative charge) or loss (positive charge) of one or more electrons. Atoms with a positive charge are known as CATIONS; those with a negative charge are ANIONS.
D008673	Metals, Alkaline Earth	Metals that constitute the group 2 (formerly group IIA) of the periodic table.	Alkaline Earth Metal,Alkaline Earth Metals,Group 2 Element,Group 2 Elements,2 Element, Group,Earth Metal, Alkaline,Earth Metals, Alkaline,Element, Group 2,Elements, Group 2,Metal, Alkaline Earth
D002614	Chelating Agents	Chemicals that bind to and remove ions from solutions. Many chelating agents function through the formation of COORDINATION COMPLEXES with METALS.	Chelating Agent,Chelator,Complexons,Metal Antagonists,Chelators,Metal Chelating Agents,Agent, Chelating,Agents, Chelating,Agents, Metal Chelating,Antagonists, Metal,Chelating Agents, Metal
D000464	Alginates	Salts and esters of ALGINIC ACID that are used as HYDROGELS; DENTAL IMPRESSION MATERIALS, and as absorbent materials for surgical dressings (BANDAGES, HYDROCOLLOID). They are also used to manufacture MICROSPHERES and NANOPARTICLES for DIAGNOSTIC REAGENT KITS and DRUG DELIVERY SYSTEMS.	Alginate,Alginic Acid, Barium Salt,Alginic Acid, Calcium Salt,Alginic Acid, Copper Salt,Alginic Acid, Potassium Salt,Alginic Acid, Sodium Salt,Alloid G,Barium Alginate,Calcium Alginate,Calginat,Copper Alginate,Kalrostat,Kalrostat 2,Kaltostat,Potassium Alginate,Sodium Alginate,Sodium Calcium Alginate,Vocoloid,Xantalgin,poly(Mannuronic Acid), Sodium Salt,Alginate, Barium,Alginate, Calcium,Alginate, Copper,Alginate, Potassium,Alginate, Sodium,Alginate, Sodium Calcium,Calcium Alginate, Sodium
D001704	Biopolymers	Polymers synthesized by living organisms. They play a role in the formation of macromolecular structures and are synthesized via the covalent linkage of biological molecules, especially AMINO ACIDS; NUCLEOTIDES; and CARBOHYDRATES.	Bioplastics,Bioplastic,Biopolymer
D015394	Molecular Structure	The location of the atoms, groups or ions relative to one another in a molecule, as well as the number, type and location of covalent bonds.	Structure, Molecular,Molecular Structures,Structures, Molecular
D056831	Coordination Complexes	Neutral or negatively charged ligands bonded to metal cations or neutral atoms. The number of ligand atoms to which the metal center is directly bonded is the metal cation's coordination number, and this number is always greater than the regular valence or oxidation number of the metal. A coordination complex can be negative, neutral, or positively charged.	Metal Complexes,Complexes, Coordination,Complexes, Metal
D020100	Hydrogels	Water swollen, rigid, 3-dimensional network of cross-linked, hydrophilic macromolecules, 20-95% water. They are used in paints, printing inks, foodstuffs, pharmaceuticals, and cosmetics. (Grant & Hackh's Chemical Dictionary, 5th ed)	Hydrogel,In Situ Hydrogel,In Situ Hydrogels,Patterned Hydrogel,Patterned Hydrogels,Hydrogel, In Situ,Hydrogel, Patterned