Biomaterial Database

Inhibition of growth and swarming of Proteus mirabilis and Proteus vulgaris by triclosan. 1987

B D Firehammer

The MICs of triclosan (2,4,4'-trichloro-2'-hydroxydiphenyl ether) and the effect on swarming were determined for 35 isolates of Proteus mirabilis and 7 isolates of P. vulgaris of animal origin. Both species were susceptible to the antimicrobial agent, and growth of all but one isolate was inhibited by less than 1 microgram/ml in broth and on agar without blood. Swarming was inhibited at triclosan concentrations two- to fourfold less than the MICs. Higher concentrations were required with blood agar than with plain agar for inhibition of growth and swarming.

UI	MeSH Term	Description	Entries
D010647	Phenyl Ethers	Ethers that are linked to a benzene ring structure.	Diphenyl Oxide,Diphenyl Oxides,Diphenyl Ethers,Ethers, Diphenyl,Ethers, Phenyl,Oxide, Diphenyl,Oxides, Diphenyl
D011513	Proteus mirabilis	A species of gram-negative, facultatively anaerobic, rod-shaped bacteria that is frequently isolated from clinical specimens. Its most common site of infection is the urinary tract.
D011514	Proteus vulgaris	A species of gram-negative, facultatively anaerobic, rod-shaped bacteria that occurs in soil, fecal matter, and sewage. It is an opportunistic pathogen and causes cystitis and pyelonephritis.
D002465	Cell Movement	The movement of cells from one location to another. Distinguish from CYTOKINESIS which is the process of dividing the CYTOPLASM of a cell.	Cell Migration,Locomotion, Cell,Migration, Cell,Motility, Cell,Movement, Cell,Cell Locomotion,Cell Motility,Cell Movements,Movements, Cell
D003470	Culture Media	Any liquid or solid preparation made specifically for the growth, storage, or transport of microorganisms or other types of cells. The variety of media that exist allow for the culturing of specific microorganisms and cell types, such as differential media, selective media, test media, and defined media. Solid media consist of liquid media that have been solidified with an agent such as AGAR or GELATIN.	Media, Culture
D014260	Triclosan	A diphenyl ether derivative used in cosmetics and toilet soaps as an antiseptic. It has some bacteriostatic and fungistatic action.	2,4,4'-Trichloro-2'-Hydroxydiphenyl Ether,2-Hydroxy-2',4,4'-trichlorodiphenyl Ether,Aquasept,Clearasil Daily Face Wash,Cliniclean,Irgasan DP 300,Irgasan DP300,Irgasan-DP300,Manusept,Microshield T,Oxy Skin Wash,Sapoderm,Ster-Zac Bath Concentrate,Tersaseptic,Trisan,pHisoHex,DP300, Irgasan,Ster Zac Bath Concentrate,SterZac Bath Concentrate