-transparent.png){kind=logo}
Non-insulin-dependent diabetes mellitus is an increasingly prevalent disease in Western and developing societies. A major metabolic abnormality of non-insulin-dependent diabetes is impaired insulin action (insulin resistance). Diets high in fat from vegetable and nonaquatic animal sources (rich in linoleic acid, an omega-6 fatty acid, and saturated fats) lead to insulin resistance. In rats fed high-fat diets, replacement of only 6 percent of the linoleic omega-6 fatty acids from safflower oil with long-chain polyunsaturated omega-3 fatty acids from fish oil prevented the development of insulin resistance. The effect was most pronounced in the liver and skeletal muscle, which have important roles in glucose supply and demand. The results may be important for therapy or prevention of non-insulin-dependent diabetes mellitus.
L H Storlien, and
E W Kraegen, and
D J Chisholm, and
G L Ford, and
D G Bruce, and
W S Pascoe
January 2015,
Journal of diabetes research,
L H Storlien, and
E W Kraegen, and
D J Chisholm, and
G L Ford, and
D G Bruce, and
W S Pascoe
January 2013,
ISRN inflammation,
L H Storlien, and
E W Kraegen, and
D J Chisholm, and
G L Ford, and
D G Bruce, and
W S Pascoe
June 1993,
Annals of the New York Academy of Sciences,
L H Storlien, and
E W Kraegen, and
D J Chisholm, and
G L Ford, and
D G Bruce, and
W S Pascoe
March 2012,
American journal of physiology. Regulatory, integrative and comparative physiology,
L H Storlien, and
E W Kraegen, and
D J Chisholm, and
G L Ford, and
D G Bruce, and
W S Pascoe
October 2008,
Zhonghua yi xue za zhi,
L H Storlien, and
E W Kraegen, and
D J Chisholm, and
G L Ford, and
D G Bruce, and
W S Pascoe
January 2024,
Biomedical research (Tokyo, Japan),
L H Storlien, and
E W Kraegen, and
D J Chisholm, and
G L Ford, and
D G Bruce, and
W S Pascoe
January 2013,
The Journal of nutritional biochemistry,
L H Storlien, and
E W Kraegen, and
D J Chisholm, and
G L Ford, and
D G Bruce, and
W S Pascoe
May 2002,
Journal of lipid research,
L H Storlien, and
E W Kraegen, and
D J Chisholm, and
G L Ford, and
D G Bruce, and
W S Pascoe
December 2014,
Diabetes,
L H Storlien, and
E W Kraegen, and
D J Chisholm, and
G L Ford, and
D G Bruce, and
W S Pascoe
November 1997,
Diabetes,
