Biomaterial Database

[Experimental study of a bacterial adhesion to titanium plates used for osteosynthesis of facial bones]. 2020

A M Sipkin, and A V Demyanova, and T V Tsareva

Moscow Regional Research and Clinical Institute, Moscow, Russia.

BACKGROUND The adhesion ability of microorganisms to the surface of titanium miniplates and screws is one of factors in the development of purulent-inflammatory complications in the postoperative period. One of the solutions to this problem is the use of an ion-plasma coating of mini-plates and screws. OBJECTIVE The aim of the study was to prove a decrease adhesion level of pathogenic and conditionally pathogenic bacterium to samples of titanium mini-plates with ion-plasma coating, compared with samples without coating. METHODS Present opinion about microbial adhesion, how the most important stage of development microbial colonization of abiotic surfaces, was been basis of this study. The strains of aerobic and facultative anaerobic pathogens, as well as the non-spore-forming (non-clostridial) obligate-anaerobic pathogens were used in the research. During the experiments the standard method for determining residual adhesion was applied. The data obtained were processed by the «Biostat 9.0» software package. For the data received by the methods of variational parametric and nonparametric statistics we used the Mann-Whitney test, taking into account the average value, error, and the number of observations (significance of differences at p<0.05). RESULTS As a result, the differences between the indices residual adhesion of strains aerobic and facultative anaerobic pathogens on the samples with and without a protective coating were statistically reliable, however, the adhesion of the individual species varied. The same differences between the indices residual adhesion were obtained among the strains of obligate anaerobic pathogens. The low level of adhesion, which was observed in the case of using the protective coating, is a very promising way of development, since these microorganisms are dangerous as the may lead to the development of purulent-inflammatory complications and the rejection of implants. CONCLUSIONS The decreased level of adhesion is a factor which reduces the microbial load during the postoperative period.

UI	MeSH Term	Description	Entries
D005147	Facial Bones	The facial skeleton, consisting of bones situated between the cranial base and the mandibular region. While some consider the facial bones to comprise the hyoid (HYOID BONE), palatine (HARD PALATE), and zygomatic (ZYGOMA) bones, MANDIBLE, and MAXILLA, others include also the lacrimal and nasal bones, inferior nasal concha, and vomer but exclude the hyoid bone. (Jablonski, Dictionary of Dentistry, 1992, p113)	Bone, Facial,Bones, Facial,Facial Bone
D001422	Bacterial Adhesion	Physicochemical property of fimbriated (FIMBRIAE, BACTERIAL) and non-fimbriated bacteria of attaching to cells, tissue, and nonbiological surfaces. It is a factor in bacterial colonization and pathogenicity.	Adhesion, Bacterial,Adhesions, Bacterial,Bacterial Adhesions
D013499	Surface Properties	Characteristics or attributes of the outer boundaries of objects, including molecules.	Properties, Surface,Property, Surface,Surface Property
D014025	Titanium	A dark-gray, metallic element of widespread distribution but occurring in small amounts with atomic number, 22, atomic weight, 47.867 and symbol, Ti; specific gravity, 4.5; used for fixation of fractures.