Analysis of factors influencing accuracy of ultrasound-based fetal weight estimation. 2020

Sujitkumar Hiwale, and Celine Firtion
Philips Research India, Philips Innovation Campus, Nagavara, Bengaluru, Karnataka, India.

BACKGROUND The primary objective of this study was to examine the impact of maternal age, parity, gestational age, fetal gender, gestational diabetes mellitus, and pregnancy-induced hypertension on the accuracy of ultrasonography-based fetal weight estimation. The secondary objective was to find the impact of a formula selection on the accuracy of fetal weight estimation. METHODS The inclusion criteria were a live-birth singleton pregnancy and the last ultrasound scan to delivery interval ≤7 days. Fetal weight was estimated using the Hadlock-4 formula. To study the concurrent impact of all the factors on the accuracy, cases were divided into two subcategories based on percentage error, with ±10% as a threshold. The accuracy of Hadlock-4 formula was compared with the two Indian population-based formulas, Hiwale-1 and Hiwale-2. RESULTS In total, 184 cases were included in the study. It was observed that the systematic error in weight estimation was significantly less in the male fetuses (8.45 ± 9.34%) in comparison to the female fetuses (11.71 ± 10.34%). The combined impact of all the factors on the accuracy was found to be nonsignificant by the multivariate analysis. The Hiwale-1 (-0.59 ± 8.75%) and Hiwale-2 (-0.65 ± 8.7%) formulas had statistically significant less errors compared to the Hadlock-4 formula (11.67 ± 7.95%). CONCLUSIONS All the studied clinical factors were found to have a limited impact on the overall accuracy of fetal weight estimation. However, the formula selection was found to have a significant impact on the accuracy, with the native population-based formulas being significantly more accurate.

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