Biomaterial Database

Adenosine deaminase activity in tuberculous pleural effusions: a diagnostic test. 1987

W F Strankinga, and J J Nauta, and J P Straub, and J Stam

Department of Pulmonology and Tuberculosis, Academic Hospital, Free University, Amsterdam, The Netherlands.

The activity of adenosine deaminase (ADA) was investigated in pleural effusions from 10 patients with tuberculous pleurisy and 76 patients with pleural effusions of other aetiology. The ADA activity in the tuberculous patients was significantly higher than in the other groups, with the exception of those with empyema. Specificity (87%) and sensitivity (100%) of this test for tuberculosis is high when a reference limit of more than 53 U/l is taken.

UI	MeSH Term	Description	Entries
D008171	Lung Diseases	Pathological processes involving any part of the LUNG.	Pulmonary Diseases,Disease, Pulmonary,Diseases, Pulmonary,Pulmonary Disease,Disease, Lung,Diseases, Lung,Lung Disease
D009700	Nucleoside Deaminases	Catalyze the hydrolysis of nucleosides with the elimination of ammonia.	Deaminases, Nucleoside
D010996	Pleural Effusion	Presence of fluid in the pleural cavity resulting from excessive transudation or exudation from the pleural surfaces. It is a sign of disease and not a diagnosis in itself.	Effusion, Pleural,Effusions, Pleural,Pleural Effusions
D012016	Reference Values	The range or frequency distribution of a measurement in a population (of organisms, organs or things) that has not been selected for the presence of disease or abnormality.	Normal Range,Normal Values,Reference Ranges,Normal Ranges,Normal Value,Range, Normal,Range, Reference,Ranges, Normal,Ranges, Reference,Reference Range,Reference Value,Value, Normal,Value, Reference,Values, Normal,Values, Reference
D004796	Clinical Enzyme Tests	Analyses for a specific enzyme activity, or of the level of a specific enzyme that is used to assess health and disease risk, for early detection of disease or disease prediction, diagnosis, and change in disease status.	Enzyme Tests, Clinical,Clinical Enzyme Test,Enzyme Test, Clinical,Test, Clinical Enzyme,Tests, Clinical Enzyme
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000243	Adenosine Deaminase	An enzyme that catalyzes the hydrolysis of ADENOSINE to INOSINE with the elimination of AMMONIA.	Adenosine Aminohydrolase,Aminohydrolase, Adenosine,Deaminase, Adenosine
D012680	Sensitivity and Specificity	Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)	Specificity,Sensitivity,Specificity and Sensitivity
D014396	Tuberculosis, Pleural	Tuberculosis of the serous membrane lining the thoracic cavity and surrounding the lungs.	Pleurisy, Tuberculous,Pleural Tuberculoses,Pleural Tuberculosis,Pleurisies, Tuberculous,Tuberculoses, Pleural,Tuberculous Pleurisies,Tuberculous Pleurisy

Related Publications

W F Strankinga, and J J Nauta, and J P Straub, and J Stam

[Adenosine deaminase activity in tuberculous and malignant pleural effusions].

January 2006, Pneumonologia i alergologia polska,

W F Strankinga, and J J Nauta, and J P Straub, and J Stam

Adenosine deaminase activity in pleural fluid--a diagnostic test of tuberculous pleural effusion.

January 1992, The Indian journal of chest diseases & allied sciences,

W F Strankinga, and J J Nauta, and J P Straub, and J Stam

The diagnostic utility of adenosine deaminase isoenzymes in tuberculous pleural effusions.

February 2009, The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease,

W F Strankinga, and J J Nauta, and J P Straub, and J Stam

Diagnostic value of adenosine deaminase activity in tuberculous effusions.

October 1990, The European respiratory journal,

W F Strankinga, and J J Nauta, and J P Straub, and J Stam

Adenosine deaminase activity in pleural effusions.

June 1986, The Journal of the Association of Physicians of India,

W F Strankinga, and J J Nauta, and J P Straub, and J Stam

Diagnostic value of pleural adenosine deaminase in tuberculous effusions of immunocompromised hosts.

July 1993, Journal of the Formosan Medical Association = Taiwan yi zhi,

W F Strankinga, and J J Nauta, and J P Straub, and J Stam

Diagnostic accuracy of interleukin-22 and adenosine deaminase for tuberculous pleural effusions.

November 2018, Current research in translational medicine,