Strategies in Infertile Azoospermic Patients with Negative Microdissection Testicular Sperm Extraction Surgery. 2023

Tharu Tharakan, and Rong Luo, and Daniel Foran, and Miles Smith, and Channa N Jayasena, and Suks Minhas
Department of Urology, Imperial Healthcare NHS Trust, Charing Cross Hospital, London, UK; Section of Investigative Medicine, Department of Medicine, Imperial College London, London, UK.

Non-obstructive azoospermia is reported to affect 1 in 100 men, and despite advances in surgical practice, the succesful sperm retrieval rate for microdissection testicular sperm extraction surgery (mTESE) is only 46%. This article reviews the potential causes for mTESE failure and provides a management strategy to guide the clinicians on how to treat this challenging cohort of patients.

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