Biomaterial Database

Phrenic Nerve Involvement in Neuralgic Amyotrophy (Parsonage-Turner Syndrome). 2020

Ellen Farr, and Dom D'Andrea, and Colin K Franz

Shirley Ryan AbilityLab, McGaw Medical Center, Northwestern University, 355 East Erie Street, 26N (Biologics), Chicago, IL 60611, USA.

Neuralgic amyotrophy is a poorly understood neuromuscular disorder affecting peripheral nerves mostly within the brachial plexus distribution but can also involve other sites including the phrenic nerve. In the classic form of the syndrome it causes proximal upper limb and neck pain on the affected side with subsequent muscle weakness that can be highly heterogeneous. Nocturnal noninvasive ventilation support is a first-line treatment after phrenic mononeuropathy. The regular monitoring of diaphragm function with spirometry and diaphragm ultrasound can help determine prognosis and inform decision-making.

UI	MeSH Term	Description	Entries
D010791	Phrenic Nerve	The motor nerve of the diaphragm. The phrenic nerve fibers originate in the cervical spinal column (mostly C4) and travel through the cervical plexus to the diaphragm.	Nerve, Phrenic,Nerves, Phrenic,Phrenic Nerves
D003964	Diaphragm	The musculofibrous partition that separates the THORACIC CAVITY from the ABDOMINAL CAVITY. Contraction of the diaphragm increases the volume of the thoracic cavity aiding INHALATION.	Respiratory Diaphragm,Diaphragm, Respiratory,Diaphragms,Diaphragms, Respiratory,Respiratory Diaphragms
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D020968	Brachial Plexus Neuritis	A syndrome associated with inflammation of the BRACHIAL PLEXUS. Clinical features include severe pain in the shoulder region which may be accompanied by MUSCLE WEAKNESS and loss of sensation in the upper extremity. This condition may be associated with VIRUS DISEASES; IMMUNIZATION; SURGERY; heroin use (see HEROIN DEPENDENCE); and other conditions. The term brachial neuralgia generally refers to pain associated with brachial plexus injury. (From Adams et al., Principles of Neurology, 6th ed, pp1355-6)	Amyotrophy, Neuralgic,Cervico-Brachial Neuralgia,Neuralgia, Amyotrophic,Neuralgic Amyotrophy,Neuritis, Brachial Plexus,Parsonage-Turner Syndrome,Shoulder-Girdle Neuropathy,Amyotrophic Neuralgia,Amyotrophy, Hereditary Neuralgic,Amyotrophy, Hereditary Neuralgic, with Predilection for Brachial Plexus,Brachial Neuralgia,Brachial Neuritis,Brachial Plexus Neuropathy, Hereditary,Cervicobrachial Neuralgia,Familial Brachial Plexus Neuritis,Hereditary Brachial Plexus Neuropathy,Hereditary Neuralgic Amyotrophy,Heredofamilial Neuritis with Brachial Plexus Predilection,Neuritis With Brachial Predilection,Parsonage-Aldren-Turner Syndrome,Shoulder Girdle Neuropathy,Amyotrophic Neuralgias,Amyotrophies, Hereditary Neuralgic,Amyotrophies, Neuralgic,Brachial Neuralgias,Brachial Neuritides,Brachial Plexus Neuritides,Cervico Brachial Neuralgia,Cervico-Brachial Neuralgias,Cervicobrachial Neuralgias,Girdle Neuropathies, Shoulder,Girdle Neuropathy, Shoulder,Hereditary Neuralgic Amyotrophies,Neuralgia, Brachial,Neuralgia, Cervico-Brachial,Neuralgia, Cervicobrachial,Neuralgias, Amyotrophic,Neuralgias, Brachial,Neuralgias, Cervico-Brachial,Neuralgias, Cervicobrachial,Neuralgic Amyotrophies,Neuralgic Amyotrophies, Hereditary,Neuralgic Amyotrophy, Hereditary,Neuritides, Brachial,Neuritides, Brachial Plexus,Neuritis, Brachial,Neuropathies, Shoulder Girdle,Neuropathies, Shoulder-Girdle,Neuropathy, Shoulder Girdle,Neuropathy, Shoulder-Girdle,Parsonage Aldren Turner Syndrome,Parsonage Turner Syndrome,Shoulder Girdle Neuropathies,Shoulder-Girdle Neuropathies,Syndrome, Parsonage-Aldren-Turner,Syndrome, Parsonage-Turner
D063087	Noninvasive Ventilation	Techniques for administering artificial respiration without the need for INTRATRACHEAL INTUBATION.	Non Invasive Ventilation,Non-Invasive Ventilation,Non Invasive Ventilations,Non-Invasive Ventilations,Noninvasive Ventilations,Ventilation, Non Invasive,Ventilation, Non-Invasive,Ventilation, Noninvasive,Ventilations, Non Invasive,Ventilations, Non-Invasive,Ventilations, Noninvasive