Biomaterial Database

On the use of fissure sealants in caries prevention. A clinical study. 1977

L Alvesalo, and R Brummer, and Y Le Bell

The aim of the present study was to clarify in the light of a clinical investigation on 6-7 years old children, some questions concerning the use of fissure sealants in public dental care. The results of the study conducted with the Nuva-Seal R (L.D. Caulk, Milford, Del.) compound suggested a caries decrease of 84 per cent one year, and 53 per cent two years after sealant application to permanent teeth. In deciduous teeth the reduction was rather similar. Totally or partially lost sealants were not reapplied or repaired during the investigation. It is obvious that the sealants are, in most cases, apt to postpone the need of restorative treatment for a limited period of time only. Postponement may, however, be considered to achieve some advantages as compared with conventional or prophylactic filling procedures.

UI	MeSH Term	Description	Entries
D010895	Pit and Fissure Sealants	Agents used to occlude dental enamel pits and fissures in the prevention of dental caries.	Dental Sealant,Dental Sealants,Fissure Sealant,Fissure Sealants,Pit And Fissure Sealant,Pit Fissure Sealant,Sealants, Tooth,Pit Fissure Sealants,Sealants, Dental,Fissure Sealant, Pit,Fissure Sealants, Pit,Sealant, Dental,Sealant, Fissure,Sealant, Pit Fissure,Sealant, Tooth,Sealants, Fissure,Sealants, Pit Fissure,Tooth Sealant,Tooth Sealants
D002648	Child	A person 6 to 12 years of age. An individual 2 to 5 years old is CHILD, PRESCHOOL.	Children
D002986	Clinical Trials as Topic	Works about pre-planned studies of the safety, efficacy, or optimum dosage schedule (if appropriate) of one or more diagnostic, therapeutic, or prophylactic drugs, devices, or techniques selected according to predetermined criteria of eligibility and observed for predefined evidence of favorable and unfavorable effects. This concept includes clinical trials conducted both in the U.S. and in other countries.	Clinical Trial as Topic
D003731	Dental Caries	Localized destruction of the tooth surface initiated by decalcification of the enamel followed by enzymatic lysis of organic structures and leading to cavity formation. If left unchecked, the cavity may penetrate the enamel and dentin and reach the pulp.	Caries, Dental,Carious Lesions,Dental Cavities,Dental Cavity,Dental Decay,Dental White Spots,Carious Dentin,Decay, Dental,Dental White Spot,White Spot, Dental,White Spots, Dental,Carious Dentins,Carious Lesion,Cavities, Dental,Cavity, Dental,Dentin, Carious,Dentins, Carious,Lesion, Carious,Lesions, Carious,Spot, Dental White,Spots, Dental White
D003764	Dental Materials	Materials used in the production of dental bases, restorations, impressions, prostheses, etc.	Dental Material,Material, Dental,Materials, Dental
D004341	Drug Evaluation	Any process by which toxicity, metabolism, absorption, elimination, preferred route of administration, safe dosage range, etc., for a drug or group of drugs is determined through clinical assessment in humans or veterinary animals.	Evaluation Studies, Drug,Drug Evaluation Studies,Drug Evaluation Study,Drug Evaluations,Evaluation Study, Drug,Evaluation, Drug,Evaluations, Drug,Studies, Drug Evaluation,Study, Drug Evaluation
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man