Hair is a barrier to physical activity engagement for Black women. Eurocentric and straight hairstyles have shown to compromise Black women's health; yet, the health implications of these hair practices have garnered little attention. This study examines the impact of natural hair on physical activity behaviors and health profiles among Black women. Sixty-nine Black women (ages 18-51) affiliated with a large predominately White institution completed demographic and hair questionnaires, Godin's Leisure-Time Exercise questionnaire, Rosenburg's self-esteem scale, and the Bankhead-Johnson hair-esteem scale. Body composition was assessed using waist circumference and body mass index. Descriptive statistics including mean, standard deviation, and percentages were employed to determine health status in each measure. Correlation analysis determined associations between each variable. Black women with natural hair were physically active, and had positive hair- and self-esteem profiles. Body composition was high; however, BMI metrics used are inappropriate for Black women. The authors conclude that natural hair may be a catalyst for Black women to improve mental and physical health. Afrocentric approaches that include affirmations of natural hairstyles are recommended to increase the effectiveness of health and physical activity promotion efforts that target Black women.