Biomaterial Database

Giant cell reparative granuloma of the hand. 1987

S M Wenner, and K Johnson

Shriners Hospital for Crippled Children, Springfield, Mass.

A case of recurrent giant cell reparative granuloma of the hand is reported. The radiographs showed a lytic, expansile lesion that extended from the secondary ossification center proximally to the articular surface distally. Treatment consisted of excision of the involved proximal phalanx and interposition bone graft. The histopathologic findings were typical for this benign, nonneoplastic process: a cellular fibrous stroma with many giant cells. The differentiation of giant cell reparative granuloma from giant cell tumor, aneurysmal bone cyst, and brown tumor of hyperparathyroidism is reviewed.

UI	MeSH Term	Description	Entries
D008297	Male		Males
D001842	Bone and Bones	A specialized CONNECTIVE TISSUE that is the main constituent of the SKELETON. The principal cellular component of bone is comprised of OSTEOBLASTS; OSTEOCYTES; and OSTEOCLASTS, while FIBRILLAR COLLAGENS and hydroxyapatite crystals form the BONE MATRIX.	Bone Tissue,Bone and Bone,Bone,Bones,Bones and Bone,Bones and Bone Tissue,Bony Apophyses,Bony Apophysis,Condyle,Apophyses, Bony,Apophysis, Bony,Bone Tissues,Condyles,Tissue, Bone,Tissues, Bone
D003937	Diagnosis, Differential	Determination of which one of two or more diseases or conditions a patient is suffering from by systematically comparing and contrasting results of diagnostic measures.	Diagnoses, Differential,Differential Diagnoses,Differential Diagnosis
D006101	Granuloma, Giant Cell	A non-neoplastic inflammatory lesion, usually of the jaw or gingiva, containing large, multinucleated cells. It includes reparative giant cell granuloma. Peripheral giant cell granuloma refers to the gingiva (giant cell epulis); central refers to the jaw.	Epulis, Giant Cell,Giant Cell Granuloma,Granuloma, Giant Cell Reparative,Epulides, Giant Cell,Peripheral Giant Cell Granuloma,Giant Cell Epulides,Giant Cell Epulis,Giant Cell Granulomas,Granulomas, Giant Cell
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000293	Adolescent	A person 13 to 18 years of age.	Adolescence,Youth,Adolescents,Adolescents, Female,Adolescents, Male,Teenagers,Teens,Adolescent, Female,Adolescent, Male,Female Adolescent,Female Adolescents,Male Adolescent,Male Adolescents,Teen,Teenager,Youths
D013933	Thumb	The first digit on the radial side of the hand which in humans lies opposite the other four.	Thumbs
D016025	Bone Transplantation	The grafting of bone from a donor site to a recipient site.	Grafting, Bone,Transplantation, Bone,Bone Grafting