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Mediators of anaphylactic reactions: Tryptase and histamine stability in whole blood. 2021

Julien Serrier, and Kathy Khoy, and Gautier Petit, and Jean-Jacques Parienti, and Dominique Laroche, and Delphine Mariotte, and Brigitte Le Mauff
Laboratoire d'Immunologie et Immunopathologie, Centre Hospitalier Universitaire de Caen, Caen, France.

UI MeSH Term Description Entries
D008407 Mast Cells Granulated cells that are found in almost all tissues, most abundantly in the skin and the gastrointestinal tract. Like the BASOPHILS, mast cells contain large amounts of HISTAMINE and HEPARIN. Unlike basophils, mast cells normally remain in the tissues and do not circulate in the blood. Mast cells, derived from the bone marrow stem cells, are regulated by the STEM CELL FACTOR. Basophils, Tissue,Basophil, Tissue,Cell, Mast,Cells, Mast,Mast Cell,Tissue Basophil,Tissue Basophils
D006632 Histamine An amine derived by enzymatic decarboxylation of HISTIDINE. It is a powerful stimulant of gastric secretion, a constrictor of bronchial smooth muscle, a vasodilator, and also a centrally acting neurotransmitter. Ceplene,Histamine Dihydrochloride,Histamine Hydrochloride,Peremin
D006636 Histamine Release The secretion of histamine from mast cell and basophil granules by exocytosis. This can be initiated by a number of factors, all of which involve binding of IgE, cross-linked by antigen, to the mast cell or basophil's Fc receptors. Once released, histamine binds to a number of different target cell receptors and exerts a wide variety of effects. Histamine Liberation,Histamine Liberations,Histamine Releases
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000707 Anaphylaxis An acute hypersensitivity reaction due to exposure to a previously encountered ANTIGEN. The reaction may include rapidly progressing URTICARIA, respiratory distress, vascular collapse, systemic SHOCK, and death. Anaphylactic Reaction,Anaphylactoid Reaction,Anaphylactoid Shock,Shock, Anaphylactic,Anaphylactic Reactions,Anaphylactic Shock,Anaphylactoid Reactions,Reaction, Anaphylactic,Reaction, Anaphylactoid,Shock, Anaphylactoid
D053802 Tryptases A family of neutral serine proteases with TRYPSIN-like activity. Tryptases are primarily found in the SECRETORY GRANULES of MAST CELLS and are released during mast cell degranulation. Tryptase,beta-Tryptases,Mast Cell Tryptase,Skin Tryptase,alpha-Tryptase,alpha-Tryptases,beta-Tryptase,delta-Tryptase,delta-Tryptases,gamma-Tryptase,gamma-Tryptases,Tryptase, Skin,alpha Tryptase,alpha Tryptases,beta Tryptase,beta Tryptases,delta Tryptase,delta Tryptases,gamma Tryptase,gamma Tryptases
D053818 Chymases A family of neutral serine proteases with CHYMOTRYPSIN-like activity. Chymases are primarily found in the SECRETORY GRANULES of MAST CELLS and are released during mast cell degranulation. Chymase,Chymase-1,Chymotrypsin-Like Protease,Chymotrypsin-Like Proteases,Chymase 1,Chymotrypsin Like Protease,Chymotrypsin Like Proteases

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