Controlled trial of the effect of cycloalliin on the fibrinolytic activity of venous blood. 1977

R K Agarwal, and H A Dewar, and D J Newell, and B Das

Cycloalliin is a natural constituent of onion, sulphur-containing but odourless. It was synthesised for this randomised double-blind study; its effect on fibribolytic activity and platelet aggregability was tested in venous blood from 18 male volunteers. It increased the former to a highly significant degree but had no effect on the latter. It was well tolerated and harmless in the single oral dosage used.

UI MeSH Term Description Entries
D008297 Male Males
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D010875 Pipecolic Acids Acids, Pipecolic
D010974 Platelet Aggregation The attachment of PLATELETS to one another. This clumping together can be induced by a number of agents (e.g., THROMBIN; COLLAGEN) and is part of the mechanism leading to the formation of a THROMBUS. Aggregation, Platelet
D002986 Clinical Trials as Topic Works about pre-planned studies of the safety, efficacy, or optimum dosage schedule (if appropriate) of one or more diagnostic, therapeutic, or prophylactic drugs, devices, or techniques selected according to predetermined criteria of eligibility and observed for predefined evidence of favorable and unfavorable effects. This concept includes clinical trials conducted both in the U.S. and in other countries. Clinical Trial as Topic
D005342 Fibrinolysis The natural enzymatic dissolution of FIBRIN. Fibrinolyses
D005343 Fibrinolytic Agents Fibrinolysin or agents that convert plasminogen to FIBRINOLYSIN. Antithrombic Drug,Antithrombotic Agent,Antithrombotic Agents,Fibrinolytic Agent,Fibrinolytic Drug,Thrombolytic Agent,Thrombolytic Agents,Thrombolytic Drug,Antithrombic Drugs,Fibrinolytic Drugs,Thrombolytic Drugs,Agent, Antithrombotic,Agent, Fibrinolytic,Agent, Thrombolytic,Agents, Antithrombotic,Drug, Antithrombic,Drug, Fibrinolytic,Drug, Thrombolytic,Drugs, Antithrombic
D006577 Heterocyclic Oxides Oxides of a ring compound having atoms other than carbon in its ring. Oxides, Heterocyclic
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults

Related Publications

R K Agarwal, and H A Dewar, and D J Newell, and B Das
June 1986, Polski tygodnik lekarski (Warsaw, Poland : 1960),
R K Agarwal, and H A Dewar, and D J Newell, and B Das
August 1979, Gastroenterology,
R K Agarwal, and H A Dewar, and D J Newell, and B Das
December 1964, Clinical science,
R K Agarwal, and H A Dewar, and D J Newell, and B Das
January 1960, Lancet (London, England),
R K Agarwal, and H A Dewar, and D J Newell, and B Das
January 1968, Laboratory practice,
R K Agarwal, and H A Dewar, and D J Newell, and B Das
August 1968, British medical journal,
R K Agarwal, and H A Dewar, and D J Newell, and B Das
January 1977, Roczniki Akademii Medycznej im. Juliana Marchlewskiego w Bialymstoku,
R K Agarwal, and H A Dewar, and D J Newell, and B Das
September 1969, Il Policlinico. Sezione pratica,
R K Agarwal, and H A Dewar, and D J Newell, and B Das
September 1967, The American journal of the medical sciences,
R K Agarwal, and H A Dewar, and D J Newell, and B Das
February 1970, Polski tygodnik lekarski (Warsaw, Poland : 1960),
Copied contents to your clipboard!