Retinal fundus image enhancement with image decomposition and visual adaptation. 2021

Jianglan Wang, and Yong-Jie Li, and Kai-Fu Yang
Department of Optometry and Vision Science, West China Hospital, Sichuan University, Chengdu, 610041, China. Electronic address: jianglan_wang@163.com.

Retinal fundus photography has been widely used to diagnose various prevalent diseases because many important diseases manifest themselves on the retina. However, the quality of fundus images obtained from practical clinical environments is not always good enough for diagnosis due to uneven illumination, blurring, low contrast, etc. In this paper, we propose a simple yet efficient method for fundus image enhancement. We first conduct image decomposition to divide the input image into three layers: base, detail, and noise layers; and then illumination correction, detail enhancement and denoising are conducted respectively at these three layers. Specifically, a simple visual adaptation model is used to correct the uneven illumination at the base layer and a weighted fusion is employed to enhance details and suppress noise and artifacts. The proposed method was evaluated on public datasets (DIARETDB0 and DIARETDB1), and also on some challenging images collected by us from the hospital. In addition, quality assessments by ophthalmologists were implemented to further verify the contribution of the proposed method in helping make diagnosis. Experimental results show that the proposed method outperforms other related methods and can simultaneously handle the tasks of illumination correction, detail enhancement and noise (and artifact) suppression.

UI MeSH Term Description Entries
D007089 Image Enhancement Improvement of the quality of a picture by various techniques, including computer processing, digital filtering, echocardiographic techniques, light and ultrastructural MICROSCOPY, fluorescence spectrometry and microscopy, scintigraphy, and in vitro image processing at the molecular level. Image Quality Enhancement,Enhancement, Image,Enhancement, Image Quality,Enhancements, Image,Enhancements, Image Quality,Image Enhancements,Image Quality Enhancements,Quality Enhancement, Image,Quality Enhancements, Image
D007091 Image Processing, Computer-Assisted A technique of inputting two-dimensional or three-dimensional images into a computer and then enhancing or analyzing the imagery into a form that is more useful to the human observer. Biomedical Image Processing,Computer-Assisted Image Processing,Digital Image Processing,Image Analysis, Computer-Assisted,Image Reconstruction,Medical Image Processing,Analysis, Computer-Assisted Image,Computer-Assisted Image Analysis,Computer Assisted Image Analysis,Computer Assisted Image Processing,Computer-Assisted Image Analyses,Image Analyses, Computer-Assisted,Image Analysis, Computer Assisted,Image Processing, Biomedical,Image Processing, Computer Assisted,Image Processing, Digital,Image Processing, Medical,Image Processings, Medical,Image Reconstructions,Medical Image Processings,Processing, Biomedical Image,Processing, Digital Image,Processing, Medical Image,Processings, Digital Image,Processings, Medical Image,Reconstruction, Image,Reconstructions, Image
D005654 Fundus Oculi The concave interior of the eye, consisting of the retina, the choroid, the sclera, the optic disk, and blood vessels, seen by means of the ophthalmoscope. (Cline et al., Dictionary of Visual Science, 4th ed) Fundus of the Eye,Ocular Fundus,Fundus, Ocular
D000465 Algorithms A procedure consisting of a sequence of algebraic formulas and/or logical steps to calculate or determine a given task. Algorithm
D016477 Artifacts Any visible result of a procedure which is caused by the procedure itself and not by the entity being analyzed. Common examples include histological structures introduced by tissue processing, radiographic images of structures that are not naturally present in living tissue, and products of chemical reactions that occur during analysis. Artefacts,Artefact,Artifact

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