The effects of olfactory bulb removal on single-pellet skilled reaching task in rats. 2021

Pierantonio Parmiani, and Cristina Lucchetti, and Gianfranco Franchi
Department of Biomedical and Specialty Surgical Sciences, Section of Human Physiology, University of Ferrara, Ferrara, Italy.

We focused on how the rat uses olfactory cues in a single-pellet reaching task, which is composed of three successive learned responses, Orient, Transport, and Withdrawal. Orient comprised: front wall detection, slot localisation, and nose poke until reach start. High-speed video-recording enabled us to describe the temporal features of this sequence in controls vs. 3-5 and 12-14 days after bilateral bulbectomy in trials with (P trial) vs. without (no-P trial) pellet. In controls, the full sequence was complete in P trials, while it was interrupted after Orient in no P-trials. After bulbectomy, the full sequence was seen in both P and no-P trials at days 3-5 and 12-14 and there was an increase in Orient duration due to the increased time in slot/shelf localisation. Unlike in controls, in anosmic rats, the first nose contact with the front wall took place below the slot/shelf level, and the number of nose touches together with the number of whisker cycles was significantly higher at 3-5 but not at 12-14 days. The relationship between nose touches and whisker cycles was linear in all experimental conditions. Bulbectomy resulted in no changes in the Transport duration or the time the paw spent out of the slot. These findings suggest that olfaction allows the animal to orient itself in pellet localisation, and offers insight into the contribution of olfaction during different stages of natural behaviour in skilled reaching task.

UI MeSH Term Description Entries
D007858 Learning Relatively permanent change in behavior that is the result of past experience or practice. The concept includes the acquisition of knowledge. Phenomenography
D009830 Olfactory Bulb Ovoid body resting on the CRIBRIFORM PLATE of the ethmoid bone where the OLFACTORY NERVE terminates. The olfactory bulb contains several types of nerve cells including the mitral cells, on whose DENDRITES the olfactory nerve synapses, forming the olfactory glomeruli. The accessory olfactory bulb, which receives the projection from the VOMERONASAL ORGAN via the vomeronasal nerve, is also included here. Accessory Olfactory Bulb,Olfactory Tract,Bulbus Olfactorius,Lateral Olfactory Tract,Main Olfactory Bulb,Olfactory Glomerulus,Accessory Olfactory Bulbs,Bulb, Accessory Olfactory,Bulb, Main Olfactory,Bulb, Olfactory,Bulbs, Accessory Olfactory,Bulbs, Main Olfactory,Bulbs, Olfactory,Glomerulus, Olfactory,Lateral Olfactory Tracts,Main Olfactory Bulbs,Olfactorius, Bulbus,Olfactory Bulb, Accessory,Olfactory Bulb, Main,Olfactory Bulbs,Olfactory Bulbs, Accessory,Olfactory Bulbs, Main,Olfactory Tract, Lateral,Olfactory Tracts,Olfactory Tracts, Lateral,Tract, Lateral Olfactory,Tract, Olfactory,Tracts, Lateral Olfactory,Tracts, Olfactory
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D012903 Smell The ability to detect scents or odors, such as the function of OLFACTORY RECEPTOR NEURONS. Olfaction,Sense of Smell,Smell Sense
D014738 Vibrissae Stiff hairs projecting from the face around the nose of most mammals, acting as touch receptors. Whiskers,Whisker
D051381 Rats The common name for the genus Rattus. Rattus,Rats, Laboratory,Rats, Norway,Rattus norvegicus,Laboratory Rat,Laboratory Rats,Norway Rat,Norway Rats,Rat,Rat, Laboratory,Rat, Norway,norvegicus, Rattus

Related Publications

Pierantonio Parmiani, and Cristina Lucchetti, and Gianfranco Franchi
January 2012, Current protocols in neuroscience,
Pierantonio Parmiani, and Cristina Lucchetti, and Gianfranco Franchi
January 1982, Reproduccion,
Pierantonio Parmiani, and Cristina Lucchetti, and Gianfranco Franchi
January 2018, Behavioural brain research,
Pierantonio Parmiani, and Cristina Lucchetti, and Gianfranco Franchi
January 2009, Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference,
Pierantonio Parmiani, and Cristina Lucchetti, and Gianfranco Franchi
April 1969, Proceedings of the National Academy of Sciences of the United States of America,
Pierantonio Parmiani, and Cristina Lucchetti, and Gianfranco Franchi
September 1980, Physiology & behavior,
Pierantonio Parmiani, and Cristina Lucchetti, and Gianfranco Franchi
September 1990, Physiology & behavior,
Pierantonio Parmiani, and Cristina Lucchetti, and Gianfranco Franchi
March 2007, Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery,
Copied contents to your clipboard!