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Localization of gamma-seminoprotein (gamma-Sm) was examined using horseradish peroxidase-labeled anti-gamma-Sm antibody (Chugai Corp. Ltd., Tokyo, Japan) by the enzyme-labeled antibody method in paraffin embedded specimens of 18 benign prostatic hyperplasias and 32 untreated prostatic cancers. The level of serum gamma-Sm was also determined by enzyme immunoassay in 10 untreated patients with prostatic cancer and 18 with benign prostatic hyperplasia. Specific gamma-Sm staining was detected in prostatic glandular epithelial cells and prostatic secretion of all specimens of benign prostatic hyperplasias and a half of the specimens of prostatic cancers. Specific gamma-Sm staining was shown to correlate with histological differentiation of the prostatic cancer, but no correlation was found between specific gamma-Sm staining and the level of serum gamma-Sm.
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Nihon Hinyokika Gakkai zasshi. The japanese journal of urology,
J Nakashima, and
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Y Nakashima, and
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M Tachibana, and
N Deguchi, and
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August 1983,
Nihon Hinyokika Gakkai zasshi. The japanese journal of urology,
J Nakashima, and
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January 1985,
Hinyokika kiyo. Acta urologica Japonica,
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April 1991,
Hinyokika kiyo. Acta urologica Japonica,
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March 1989,
Hinyokika kiyo. Acta urologica Japonica,
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Rinsho byori. The Japanese journal of clinical pathology,
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October 1987,
Nihon hoigaku zasshi = The Japanese journal of legal medicine,
J Nakashima, and
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