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A new picrotoxane-type sesquiterpene from Dendrobium nobile Lindl. 2022
Pei Wang, and
Xin Chen, and
Cai-Hong Cai, and
Fan-Dong Kong, and
Sheng-Zhuo Huang, and
Jing-Zhe Yuan, and
Xing-Lian Xu, and
Wen-Li Mei, and
Hao-Fu Dai
Hainan Key Laboratory of Research and Development of Natural Product from Li Folk Medicine, Hainan Institute for Tropical Agricultural Resources, Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou, PR China.
A picrotoxane-type sesquiterpene, dendroterpene E (1), together with five benzene derivatives (2-6), were isolated from the stems of Dendrobium nobile Lindl. Their structures were elucidated by spectroscopic analysis and X-ray diffraction analysis. Compound 1 was a new picrotoxane-type sesquiterpene with a C-9/C-1/O/C-11 oxetane ring, which was first encountered in this type of compounds. Compounds 1-3 exhibited inhibitory activities against α-glycosidase.
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