Two-Source Capture-Recapture Method to Estimate the Incidence of Acute Flaccid Paralysis in the Marches Region (Italy). 2020

Pamela Barbadoro, and Aurora Luciani, and Matteo Ciotti, and Marcello Mario D'Errico, and On Behalf Of The Afp Working Collaborative Group
Department of Biomedical Science and Public Health, Università Politecnica delle Marche, via Tronto 10/A, 6, 60121 Ancona, Italy.

A combination of high infant immunization coverage and surveillance of acute flaccid paralysis (AFP) cases, plays a critical role in polio eradication. This study aimed to estimate the incidence of AFP, to evaluate the completeness of AFP ascertainment during the years, age groups and gender, and to define the main associated diagnosis among children aged under 15 in the Marches region of Italy. Analysis was performed on data from the active AFP surveillance system and the hospital discharge records in the 2006-2014 period. The two-source capture-recapture method was applied. After cross-validation, 30 AFP compatible conditions as defined by the WHO were identified, with an incidence estimate of 1.91 cases of AFP per 100,000 children under 15 years (95% CI = 1.4-2.6/100,000). Guillain-Barrè syndrome was the most common diagnosis. A significant difference (p < 0.05) has been registered in the estimated probability of case ascertainment in females. The reasons for the lower reporting of cases in females are unknown. Specific research and the implementation of a more sensitive surveillance system are essential in verifying potential inequalities and to succeed in the polio eradication initiative.

UI MeSH Term Description Entries
D007223 Infant A child between 1 and 23 months of age. Infants
D007231 Infant, Newborn An infant during the first 28 days after birth. Neonate,Newborns,Infants, Newborn,Neonates,Newborn,Newborn Infant,Newborn Infants
D007558 Italy A country in southern Europe, a peninsula extending into the central Mediterranean Sea, northeast of Tunisia. The capital is Rome. Sardinia
D008297 Male Males
D009187 Myelitis Inflammation of the spinal cord. Relatively common etiologies include infections; AUTOIMMUNE DISEASES; SPINAL CORD; and ischemia (see also SPINAL CORD VASCULAR DISEASES). Clinical features generally include weakness, sensory loss, localized pain, incontinence, and other signs of autonomic dysfunction. Myelopathy, Inflammatory,Spinal Cord Inflammation,Subacute Necrotizing Myelitis,Infectious Myelitis,Inflammation, Spinal Cord,Inflammations, Spinal Cord,Inflammatory Myelopathies,Inflammatory Myelopathy,Myelitides,Myelitides, Subacute Necrotizing,Myelitis, Infectious,Myelitis, Subacute Necrotizing,Myelopathies, Inflammatory,Necrotizing Myelitides, Subacute,Necrotizing Myelitis, Subacute,Spinal Cord Inflammations,Subacute Necrotizing Myelitides
D009468 Neuromuscular Diseases A general term encompassing lower MOTOR NEURON DISEASE; PERIPHERAL NERVOUS SYSTEM DISEASES; and certain MUSCULAR DISEASES. Manifestations include MUSCLE WEAKNESS; FASCICULATION; muscle ATROPHY; SPASM; MYOKYMIA; MUSCLE HYPERTONIA, myalgias, and MUSCLE HYPOTONIA. Amyotonia Congenita,Oppenheim Disease,Cramp-Fasciculation Syndrome,Fasciculation-Cramp Syndrome, Benign,Foley-Denny-Brown Syndrome,Oppenheim's Disease,Benign Fasciculation-Cramp Syndrome,Benign Fasciculation-Cramp Syndromes,Cramp Fasciculation Syndrome,Cramp-Fasciculation Syndromes,Fasciculation Cramp Syndrome, Benign,Fasciculation-Cramp Syndromes, Benign,Foley Denny Brown Syndrome,Neuromuscular Disease,Oppenheims Disease,Syndrome, Cramp-Fasciculation,Syndrome, Foley-Denny-Brown,Syndromes, Cramp-Fasciculation
D010243 Paralysis A general term most often used to describe severe or complete loss of muscle strength due to motor system disease from the level of the cerebral cortex to the muscle fiber. This term may also occasionally refer to a loss of sensory function. (From Adams et al., Principles of Neurology, 6th ed, p45) Palsy,Plegia,Todd Paralysis,Todd's Paralysis,Palsies,Paralyses,Paralysis, Todd,Paralysis, Todd's,Plegias,Todds Paralysis
D011051 Poliomyelitis An acute infectious disease of humans, particularly children, caused by any of three serotypes of human poliovirus (POLIOVIRUS). Usually the infection is limited to the gastrointestinal tract and nasopharynx, and is often asymptomatic. The central nervous system, primarily the spinal cord, may be affected, leading to rapidly progressive paralysis, coarse FASCICULATION and hyporeflexia. Motor neurons are primarily affected. Encephalitis may also occur. The virus replicates in the nervous system, and may cause significant neuronal loss, most notably in the spinal cord. A rare related condition, nonpoliovirus poliomyelitis, may result from infections with nonpoliovirus enteroviruses. (From Adams et al., Principles of Neurology, 6th ed, pp764-5) Infantile Paralysis,Polio,Poliomyelitis, Nonpoliovirus,Poliomyelitis, Preparalytic,Encephalitis, Polio,Epidemic Acute Poliomyelitis,Polio Encephalitis,Poliomyelitis Infection,Poliomyelitis, Acute,Acute Poliomyelitis,Acute Poliomyelitis, Epidemic,Infection, Poliomyelitis,Infections, Poliomyelitis,Nonpoliovirus Poliomyelitis,Paralysis, Infantile,Poliomyelitides, Preparalytic,Poliomyelitis Infections,Poliomyelitis, Epidemic Acute,Polios,Preparalytic Poliomyelitis
D011159 Population Surveillance Ongoing scrutiny of a population (general population, study population, target population, etc.), generally using methods distinguished by their practicability, uniformity, and frequently their rapidity, rather than by complete accuracy. Surveillance, Population
D002648 Child A person 6 to 12 years of age. An individual 2 to 5 years old is CHILD, PRESCHOOL. Children

Related Publications

Pamela Barbadoro, and Aurora Luciani, and Matteo Ciotti, and Marcello Mario D'Errico, and On Behalf Of The Afp Working Collaborative Group
January 2002, Bulletin of the World Health Organization,
Pamela Barbadoro, and Aurora Luciani, and Matteo Ciotti, and Marcello Mario D'Errico, and On Behalf Of The Afp Working Collaborative Group
October 2008, BMC infectious diseases,
Pamela Barbadoro, and Aurora Luciani, and Matteo Ciotti, and Marcello Mario D'Errico, and On Behalf Of The Afp Working Collaborative Group
October 2001, European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP),
Pamela Barbadoro, and Aurora Luciani, and Matteo Ciotti, and Marcello Mario D'Errico, and On Behalf Of The Afp Working Collaborative Group
May 2022, Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology,
Pamela Barbadoro, and Aurora Luciani, and Matteo Ciotti, and Marcello Mario D'Errico, and On Behalf Of The Afp Working Collaborative Group
January 2000, European journal of epidemiology,
Pamela Barbadoro, and Aurora Luciani, and Matteo Ciotti, and Marcello Mario D'Errico, and On Behalf Of The Afp Working Collaborative Group
May 2000, Alcoholism, clinical and experimental research,
Pamela Barbadoro, and Aurora Luciani, and Matteo Ciotti, and Marcello Mario D'Errico, and On Behalf Of The Afp Working Collaborative Group
January 2016, Western Pacific surveillance and response journal : WPSAR,
Pamela Barbadoro, and Aurora Luciani, and Matteo Ciotti, and Marcello Mario D'Errico, and On Behalf Of The Afp Working Collaborative Group
January 2018, Neuroepidemiology,
Pamela Barbadoro, and Aurora Luciani, and Matteo Ciotti, and Marcello Mario D'Errico, and On Behalf Of The Afp Working Collaborative Group
September 2021, medRxiv : the preprint server for health sciences,
Pamela Barbadoro, and Aurora Luciani, and Matteo Ciotti, and Marcello Mario D'Errico, and On Behalf Of The Afp Working Collaborative Group
March 2022, Influenza and other respiratory viruses,
Copied contents to your clipboard!