ESBL-producing Escherichia coli and Klebsiella pneumoniae from health-care institutions in Mexico. 2021

Viridiana Gallegos-Miranda, and Ulises Garza-Ramos, and Enrique Bolado-Martínez, and Moisés Navarro-Navarro, and Katya Rocío Félix-Murray, and Maria Del Carmen Candia-Plata, and Guillermina Sanchez-Martinez, and Josefina Dúran-Bedolla, and Jesús Silva-Sánchez
Maestría en Ciencias de la Salud, Universidad de Sonora, Hermosillo, México.

We investigated the phenotypic and molecular characteristics of Extended-Spectrum-β-lactamase (ESBL)-producing Escherichia coli and Klebsiella pneumoniae clinical isolates from four health-care institutions in Hermosillo, Sonora, Mexico. ESBL-producing isolates were collected from February to August 2016. The prevalence of ESBL-producing E. coli and K. pneumoniae was 11.9 and 8.7%, respectively. High dissemination of resistance to ciprofloxacin (88%), trimethoprim/sulfamethoxazole (72%) and aminoglycosides (59%) were detected, as well as susceptibility to meropenem, amikacin and tigecycline. The ESBL found variants were CTX-M-1 (88%) and CTX-M-9 (5%). The plasmid-mediated quinolone resistance (PMQR) gene aac(6´)-Ib-cr was identified in 62% of a representative sample, whereas the qnrB and qnrS genes were detected in 49% of the isolates. PFGE analyses detected many unrelated clones among the hospital or community isolates. A constant programme of epidemiological surveillance is recommended to understand the dynamics of bacterial resistance to both cephalosporin as well as the fluoroquinolone family of antibiotics.

UI MeSH Term Description Entries
D007711 Klebsiella pneumoniae Gram-negative, non-motile, capsulated, gas-producing rods found widely in nature and associated with urinary and respiratory infections in humans. Bacillus pneumoniae,Bacterium pneumoniae crouposae,Hyalococcus pneumoniae,Klebsiella pneumoniae aerogenes,Klebsiella rhinoscleromatis
D008800 Mexico A country in NORTH AMERICA, bordering the Caribbean Sea and the Gulf of Mexico, between BELIZE and the UNITED STATES, and bordering the North Pacific Ocean, between Guatemala and the UNITED STATES.
D008826 Microbial Sensitivity Tests Any tests that demonstrate the relative efficacy of different chemotherapeutic agents against specific microorganisms (i.e., bacteria, fungi, viruses). Bacterial Sensitivity Tests,Drug Sensitivity Assay, Microbial,Minimum Inhibitory Concentration,Antibacterial Susceptibility Breakpoint Determination,Antibiogram,Antimicrobial Susceptibility Breakpoint Determination,Bacterial Sensitivity Test,Breakpoint Determination, Antibacterial Susceptibility,Breakpoint Determination, Antimicrobial Susceptibility,Fungal Drug Sensitivity Tests,Fungus Drug Sensitivity Tests,Sensitivity Test, Bacterial,Sensitivity Tests, Bacterial,Test, Bacterial Sensitivity,Tests, Bacterial Sensitivity,Viral Drug Sensitivity Tests,Virus Drug Sensitivity Tests,Antibiograms,Concentration, Minimum Inhibitory,Concentrations, Minimum Inhibitory,Inhibitory Concentration, Minimum,Inhibitory Concentrations, Minimum,Microbial Sensitivity Test,Minimum Inhibitory Concentrations,Sensitivity Test, Microbial,Sensitivity Tests, Microbial,Test, Microbial Sensitivity,Tests, Microbial Sensitivity
D010641 Phenotype The outward appearance of the individual. It is the product of interactions between genes, and between the GENOTYPE and the environment. Phenotypes
D004926 Escherichia coli A species of gram-negative, facultatively anaerobic, rod-shaped bacteria (GRAM-NEGATIVE FACULTATIVELY ANAEROBIC RODS) commonly found in the lower part of the intestine of warm-blooded animals. It is usually nonpathogenic, but some strains are known to produce DIARRHEA and pyogenic infections. Pathogenic strains (virotypes) are classified by their specific pathogenic mechanisms such as toxins (ENTEROTOXIGENIC ESCHERICHIA COLI), etc. Alkalescens-Dispar Group,Bacillus coli,Bacterium coli,Bacterium coli commune,Diffusely Adherent Escherichia coli,E coli,EAggEC,Enteroaggregative Escherichia coli,Enterococcus coli,Diffusely Adherent E. coli,Enteroaggregative E. coli,Enteroinvasive E. coli,Enteroinvasive Escherichia coli
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D001618 beta-Lactamases Enzymes found in many bacteria which catalyze the hydrolysis of the amide bond in the beta-lactam ring. Well known antibiotics destroyed by these enzymes are penicillins and cephalosporins. beta-Lactamase,beta Lactamase,beta Lactamases
D024901 Drug Resistance, Multiple, Bacterial The ability of bacteria to resist or to become tolerant to several structurally and functionally distinct drugs simultaneously. This resistance may be acquired through gene mutation or foreign DNA in transmissible plasmids (R FACTORS). Drug Resistance, Extensive, Bacterial,Drug Resistance, Extensively, Bacterial,Extensive Antibacterial Drug Resistance,Extensively Antibacterial Drug Resistance,Multidrug Resistance, Bacterial,Multiple Antibacterial Drug Resistance,Bacterial Multidrug Resistance,Bacterial Multidrug Resistances,Resistance, Bacterial Multidrug

Related Publications

Viridiana Gallegos-Miranda, and Ulises Garza-Ramos, and Enrique Bolado-Martínez, and Moisés Navarro-Navarro, and Katya Rocío Félix-Murray, and Maria Del Carmen Candia-Plata, and Guillermina Sanchez-Martinez, and Josefina Dúran-Bedolla, and Jesús Silva-Sánchez
September 2014, Journal of infection in developing countries,
Viridiana Gallegos-Miranda, and Ulises Garza-Ramos, and Enrique Bolado-Martínez, and Moisés Navarro-Navarro, and Katya Rocío Félix-Murray, and Maria Del Carmen Candia-Plata, and Guillermina Sanchez-Martinez, and Josefina Dúran-Bedolla, and Jesús Silva-Sánchez
January 2019, International journal of medical microbiology : IJMM,
Viridiana Gallegos-Miranda, and Ulises Garza-Ramos, and Enrique Bolado-Martínez, and Moisés Navarro-Navarro, and Katya Rocío Félix-Murray, and Maria Del Carmen Candia-Plata, and Guillermina Sanchez-Martinez, and Josefina Dúran-Bedolla, and Jesús Silva-Sánchez
February 2005, The Japanese journal of antibiotics,
Viridiana Gallegos-Miranda, and Ulises Garza-Ramos, and Enrique Bolado-Martínez, and Moisés Navarro-Navarro, and Katya Rocío Félix-Murray, and Maria Del Carmen Candia-Plata, and Guillermina Sanchez-Martinez, and Josefina Dúran-Bedolla, and Jesús Silva-Sánchez
September 2019, MicrobiologyOpen,
Viridiana Gallegos-Miranda, and Ulises Garza-Ramos, and Enrique Bolado-Martínez, and Moisés Navarro-Navarro, and Katya Rocío Félix-Murray, and Maria Del Carmen Candia-Plata, and Guillermina Sanchez-Martinez, and Josefina Dúran-Bedolla, and Jesús Silva-Sánchez
June 2018, Infection control and hospital epidemiology,
Viridiana Gallegos-Miranda, and Ulises Garza-Ramos, and Enrique Bolado-Martínez, and Moisés Navarro-Navarro, and Katya Rocío Félix-Murray, and Maria Del Carmen Candia-Plata, and Guillermina Sanchez-Martinez, and Josefina Dúran-Bedolla, and Jesús Silva-Sánchez
February 2023, Microorganisms,
Viridiana Gallegos-Miranda, and Ulises Garza-Ramos, and Enrique Bolado-Martínez, and Moisés Navarro-Navarro, and Katya Rocío Félix-Murray, and Maria Del Carmen Candia-Plata, and Guillermina Sanchez-Martinez, and Josefina Dúran-Bedolla, and Jesús Silva-Sánchez
April 2021, Journal of infection in developing countries,
Viridiana Gallegos-Miranda, and Ulises Garza-Ramos, and Enrique Bolado-Martínez, and Moisés Navarro-Navarro, and Katya Rocío Félix-Murray, and Maria Del Carmen Candia-Plata, and Guillermina Sanchez-Martinez, and Josefina Dúran-Bedolla, and Jesús Silva-Sánchez
January 2008, Indian journal of medical microbiology,
Viridiana Gallegos-Miranda, and Ulises Garza-Ramos, and Enrique Bolado-Martínez, and Moisés Navarro-Navarro, and Katya Rocío Félix-Murray, and Maria Del Carmen Candia-Plata, and Guillermina Sanchez-Martinez, and Josefina Dúran-Bedolla, and Jesús Silva-Sánchez
October 2025, Acta microbiologica et immunologica Hungarica,
Viridiana Gallegos-Miranda, and Ulises Garza-Ramos, and Enrique Bolado-Martínez, and Moisés Navarro-Navarro, and Katya Rocío Félix-Murray, and Maria Del Carmen Candia-Plata, and Guillermina Sanchez-Martinez, and Josefina Dúran-Bedolla, and Jesús Silva-Sánchez
December 2019, The Pediatric infectious disease journal,
Copied contents to your clipboard!