Biomaterial Database

Corynebacterium vaginale. 1977

W E Dunkelberg

Corynebacterium vaginale is a sexually transmitted organism which was first recognized in 1953. It appears to utilize glycogen stored in vaginal epithelial cells, causing a malodorous vaginal discharge characterized by an abnormally high pH (5.0 to 5.5) and composed mainly of epithelial cells and hordes of bacilli. Infected men are asymptomatic, carry the organism for an unknown period of time, and transmit it through intercourse. The organism requires five B-vitamins, purines, pyrimidines, and a fermentable carbohydrate; neither factors X nor V are required. It is not a member of genus Haemophilus and is not likely to be a Corynebacterium. Appearing mainly Gram-negative, it has many characteristics of Gram-positive organisms including its pattern of sensitivity to antibiotics and the possession of certain enzyme systems. As the cause of bacterial vaginitis, C. vaginale may be the most prevalent sexually-transmitted organism.

UI	MeSH Term	Description	Entries
D008722	Methods	A series of steps taken in order to conduct research.	Techniques,Methodological Studies,Methodological Study,Procedures,Studies, Methodological,Study, Methodological,Method,Procedure,Technique
D009626	Terminology as Topic	Works about the terms, expressions, designations, or symbols used in a particular science, discipline, or specialized subject area.	Etymology,Nomenclature as Topic,Etymologies
D004352	Drug Resistance, Microbial	The ability of microorganisms, especially bacteria, to resist or to become tolerant to chemotherapeutic agents, antimicrobial agents, or antibiotics. This resistance may be acquired through gene mutation or foreign DNA in transmissible plasmids (R FACTORS).	Antibiotic Resistance,Antibiotic Resistance, Microbial,Antimicrobial Resistance, Drug,Antimicrobial Drug Resistance,Antimicrobial Drug Resistances,Antimicrobial Resistances, Drug,Drug Antimicrobial Resistance,Drug Antimicrobial Resistances,Drug Resistances, Microbial,Resistance, Antibiotic,Resistance, Drug Antimicrobial,Resistances, Drug Antimicrobial
D005260	Female		Females
D006190	Haemophilus	A genus of PASTEURELLACEAE that consists of several species occurring in animals and humans. Its organisms are described as gram-negative, facultatively anaerobic, coccobacillus or rod-shaped, and nonmotile.	Hemophilus
D006192	Haemophilus Infections	Infections with bacteria of the genus HAEMOPHILUS.	Hemophilus Infections,Haemophilus influenzae Infection,Haemophilus influenzae Type b Infection,Hib Infection,Infections, Haemophilus,Infections, Hemophilus,Haemophilus Infection,Haemophilus influenzae Infections,Hemophilus Infection,Hib Infections,Infection, Haemophilus,Infection, Haemophilus influenzae,Infection, Hemophilus,Infection, Hib
D006194	Gardnerella vaginalis	A species in the genus GARDNERELLA previously classified as Haemophilus vaginalis. This bacterium, also isolated from the female genital tract of healthy women, is implicated in the cause of bacterial vaginosis (VAGINOSIS, BACTERIAL).	Haemophilus vaginalis,Corynebacterium vaginale,Hemophilus vaginalis
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D012749	Sexually Transmitted Diseases	Diseases due to or propagated by sexual contact.	Venereal Diseases,STDs,STIs,Sexually Transmitted Infections,Disease, Sexually Transmitted,Disease, Venereal,Diseases, Sexually Transmitted,Diseases, Venereal,Infection, Sexually Transmitted,Infections, Sexually Transmitted,STI,Sexually Transmitted Disease,Sexually Transmitted Infection,Transmitted Infection, Sexually,Transmitted Infections, Sexually,Venereal Disease
D014627	Vaginitis	Inflammation of the vagina characterized by pain and a purulent discharge.	Vaginitides