-transparent.png){kind=logo}
Monocyte-enriched preparations derived from peripheral blood leukocytes of atopics were probed via a cocktail comprising peroxidase-conjugated (Fab1)2 fragments of two monoclonal antibodies against human IgE. Reaction product indicative of intracellular IgE was identified by electron microscopy in both large and small vacuoles, and at high magnification exhibited a characteristic granular deposition pattern consistent with highly concentrated (perhaps insolublized) material. IgE-containing vacuoles were observed with comparable frequency to those containing IgG, despite the greater than 10,000-fold relative excess of the latter in serum suggesting highly selective uptake of IgE by the monocytes. These results are similar to those reported recently for IgA in human milk macrophages.
K J Turner, and
A Marzo, and
B J Holt, and
A Wharton, and
J M Papadimitriou, and
K J Cameron, and
N P Siemensma, and
P G Holt
January 1985,
Clinical allergy,
K J Turner, and
A Marzo, and
B J Holt, and
A Wharton, and
J M Papadimitriou, and
K J Cameron, and
N P Siemensma, and
P G Holt
December 1991,
Journal of dermatological science,
K J Turner, and
A Marzo, and
B J Holt, and
A Wharton, and
J M Papadimitriou, and
K J Cameron, and
N P Siemensma, and
P G Holt
January 1989,
International archives of allergy and applied immunology,
K J Turner, and
A Marzo, and
B J Holt, and
A Wharton, and
J M Papadimitriou, and
K J Cameron, and
N P Siemensma, and
P G Holt
January 2002,
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology,
K J Turner, and
A Marzo, and
B J Holt, and
A Wharton, and
J M Papadimitriou, and
K J Cameron, and
N P Siemensma, and
P G Holt
April 1990,
The Histochemical journal,
K J Turner, and
A Marzo, and
B J Holt, and
A Wharton, and
J M Papadimitriou, and
K J Cameron, and
N P Siemensma, and
P G Holt
January 1985,
International archives of allergy and applied immunology,
K J Turner, and
A Marzo, and
B J Holt, and
A Wharton, and
J M Papadimitriou, and
K J Cameron, and
N P Siemensma, and
P G Holt
January 1976,
Laboratory investigation; a journal of technical methods and pathology,
K J Turner, and
A Marzo, and
B J Holt, and
A Wharton, and
J M Papadimitriou, and
K J Cameron, and
N P Siemensma, and
P G Holt
September 1980,
Journal of immunology (Baltimore, Md. : 1950),
K J Turner, and
A Marzo, and
B J Holt, and
A Wharton, and
J M Papadimitriou, and
K J Cameron, and
N P Siemensma, and
P G Holt
November 1991,
Arerugi = [Allergy],
K J Turner, and
A Marzo, and
B J Holt, and
A Wharton, and
J M Papadimitriou, and
K J Cameron, and
N P Siemensma, and
P G Holt
November 1991,
The American journal of pathology,
