A Case of Endobronchial Aspergilloma Coexisting With Lung Adenocarcinoma. 2020

Halim El Hage, and Leon Fagel
Pulmonary and Critical Care Medicine, Holy Redeemer Hospital and Medical Center, Meadowbrook, USA.

Aspergillus species can cause a variety of lung diseases. Endobronchial aspergilloma is a rare clinical entity rarely encountered and often not included in the classification of Aspergillus lung diseases.  An 82-year-old woman presented to the outpatient setting with wheezing, shortness of breath, and productive cough. CT of the chest showed the presence of airway enlargement in a finger in glove pattern in the right upper lobe suggestive of allergic bronchopulmonary aspergillosis. Despite adequate treatment the abnormality persisted on repeat imaging. Bronchoscopy with biopsies eventually revealed the presence of hyphal elements suggestive of Aspergillus and poorly differentiated adenocarcinoma. Endobronchial aspergilloma is rare and not included in the classification of Aspergillus lung diseases. It is thought to result from airway colonization by Aspergillus species. Occasionally it can obscure an underlying lung carcinoma and thus delay the diagnosis. Diagnosis is made by pathological examination of biopsy specimens. Optimal treatment is not well established.

UI MeSH Term Description Entries

Related Publications

Halim El Hage, and Leon Fagel
January 2008, Mikrobiyoloji bulteni,
Halim El Hage, and Leon Fagel
June 2000, Yonsei medical journal,
Halim El Hage, and Leon Fagel
January 2016, Respiratory medicine case reports,
Halim El Hage, and Leon Fagel
October 2020, Respirology case reports,
Halim El Hage, and Leon Fagel
January 2014, International journal of clinical and experimental pathology,
Halim El Hage, and Leon Fagel
September 2005, The Japanese journal of thoracic and cardiovascular surgery : official publication of the Japanese Association for Thoracic Surgery = Nihon Kyobu Geka Gakkai zasshi,
Halim El Hage, and Leon Fagel
March 2020, Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia,
Halim El Hage, and Leon Fagel
June 2012, The American journal of the medical sciences,
Halim El Hage, and Leon Fagel
January 2011, Tuberkuloz ve toraks,
Copied contents to your clipboard!