Haemoglobin estimation--reliability of the copper sulphate specific gravity v. the cyanmethaemoglobin colorimetric method. 1988

W M Politzer, and W M Myburgh, and J F van der Merwe
Department of Haematology, Medical University of Southern Africa, Pretoria.

Automated colorimetric and copper sulphate (4 solutions with different specific gravities) methods were used to examine 218 blood specimens. The correlation between the two was high (r = 0.82)--proving that the copper sulphate method is reliable for haemoglobin screening. Copper sulphate gives better results in the higher haemoglobin region, which includes the majority of healthy people. In the lower haemoglobin region this method generally gives lower results than the cyanmethaemoglobin method. Copper sulphate is also by far the cheapest means currently available for mass screening.

UI MeSH Term Description Entries
D003124 Colorimetry Any technique by which an unknown color is evaluated in terms of standard colors. The technique may be visual, photoelectric, or indirect by means of spectrophotometry. It is used in chemistry and physics. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
D003300 Copper A heavy metal trace element with the atomic symbol Cu, atomic number 29, and atomic weight 63.55. Copper-63,Copper 63
D006452 Hemoglobinometry Measurement of hemoglobin concentration in blood. Hemoglobinometries
D006454 Hemoglobins The oxygen-carrying proteins of ERYTHROCYTES. They are found in all vertebrates and some invertebrates. The number of globin subunits in the hemoglobin quaternary structure differs between species. Structures range from monomeric to a variety of multimeric arrangements. Eryhem,Ferrous Hemoglobin,Hemoglobin,Hemoglobin, Ferrous
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D013046 Specific Gravity The ratio of the density of a material to the density of some standard material, such as water or air, at a specified temperature. Relative Density,Densities, Relative,Density, Relative,Gravities, Specific,Gravity, Specific,Relative Densities,Specific Gravities
D019327 Copper Sulfate A sulfate salt of copper. It is a potent emetic and is used as an antidote for poisoning by phosphorus. It also can be used to prevent the growth of algae. Cupric Sulfate,Blue Vitriol,Sulfate, Copper,Sulfate, Cupric,Vitriol, Blue

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