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We developed an apparatus for automated morphometry of the corneal endothelium, which was photographed through a specular microscope connected to a video camera, and the images were stored on a video tape. The clearest stationary image was input into an image analyser to determine automatically the cell boundaries. Although human interaction is generally necessary, the mean time required to complete this procedure was about 13 minutes, based on the results of the 30 normal eyes, and the time needed for manual correction was about 4 minutes. The mean cell area obtained by this method correlated well (r = 0.9335) with that obtained by tracing the same images. This apparatus is clinically useful for immediately obtaining the mean cell area of corneal endothelium and will extend the application of specular microscopy to the routine clinical setting.
O Nishi, and
K Hanasaki
January 1987,
Nippon Ganka Gakkai zasshi,
O Nishi, and
K Hanasaki
January 1993,
Documenta ophthalmologica. Advances in ophthalmology,
O Nishi, and
K Hanasaki
February 1971,
Lakartidningen,
O Nishi, and
K Hanasaki
December 1967,
Michigan medicine,
O Nishi, and
K Hanasaki
November 1968,
[Kango kyoiku] Japanese journal of nurses' education,
O Nishi, and
K Hanasaki
May 1983,
[Kango kyoiku] Japanese journal of nurses' education,
O Nishi, and
K Hanasaki
May 1983,
[Kango kyoiku] Japanese journal of nurses' education,
O Nishi, and
K Hanasaki
January 1992,
Nihon Igaku Hoshasen Gakkai zasshi. Nippon acta radiologica,
O Nishi, and
K Hanasaki
November 2004,
Optometry and vision science : official publication of the American Academy of Optometry,
O Nishi, and
K Hanasaki
January 1970,
The American journal of occupational therapy : official publication of the American Occupational Therapy Association,
