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By feeding a regular laboratory chow, sand rats (Psammomys obesus) from our breeding colony gained different body weights, though they received approximately the same quantity of calories. Sand rats, reaching a body weight above 160 g (group B) showed significantly increased blood glucose values in contrast to the animals with a body weight under 160 g (group A). Isolated pancreatic islets of these two groups of sand rats were incubated with [3H]-leucine to study the incorporation of this amino acid into proinsulin and insulin. The incorporation into proteins of pancreatic islets of sand rats of group B was stimulated by 0.45 mg and 3.0 mg/ml glucose. In group A there was no further stimulation from 0.45 mg to 3.0 mg/ml glucose. Insulin secretion could be stimulated by glucose in both groups, but the stimulation was stronger in group B than in group A.
B Wilke, and
H Jahr, and
S Schmidt, and
H Schäfer, and
D Gottschling, and
H Fiedler, and
H Zühlke
April 1979,
Endokrinologie,
B Wilke, and
H Jahr, and
S Schmidt, and
H Schäfer, and
D Gottschling, and
H Fiedler, and
H Zühlke
January 1979,
Zeitschrift fur mikroskopisch-anatomische Forschung,
B Wilke, and
H Jahr, and
S Schmidt, and
H Schäfer, and
D Gottschling, and
H Fiedler, and
H Zühlke
December 1975,
Endokrinologie,
B Wilke, and
H Jahr, and
S Schmidt, and
H Schäfer, and
D Gottschling, and
H Fiedler, and
H Zühlke
January 1981,
Cellular and molecular biology, including cyto-enzymology,
B Wilke, and
H Jahr, and
S Schmidt, and
H Schäfer, and
D Gottschling, and
H Fiedler, and
H Zühlke
January 1975,
Acta histochemica,
B Wilke, and
H Jahr, and
S Schmidt, and
H Schäfer, and
D Gottschling, and
H Fiedler, and
H Zühlke
October 1976,
Endokrinologie,
B Wilke, and
H Jahr, and
S Schmidt, and
H Schäfer, and
D Gottschling, and
H Fiedler, and
H Zühlke
January 1976,
European journal of clinical investigation,
B Wilke, and
H Jahr, and
S Schmidt, and
H Schäfer, and
D Gottschling, and
H Fiedler, and
H Zühlke
January 1981,
Acta histochemica,
B Wilke, and
H Jahr, and
S Schmidt, and
H Schäfer, and
D Gottschling, and
H Fiedler, and
H Zühlke
January 1977,
Endokrinologie,
B Wilke, and
H Jahr, and
S Schmidt, and
H Schäfer, and
D Gottschling, and
H Fiedler, and
H Zühlke
January 1977,
Acta histochemica,
