[Effect of danazol on the function of the estrogen and progesterone receptor systems of the human endometrium]. 1988

L V Adamian, and M L Alekseeva, and N N Zhukova, and L S Minina, and E A Novikov

Quantity of estrogen- and progesterone-specific binding sites was measured in endometrial tissues of 10 females treated with danazol during 3 month in a dose of 400 mg per day after surgical treatment for endometriosis. It was demonstrated that the amount of estrogen receptors in endometrium of the patients was the same as in endometrial tissue of healthy females but the quantity of nuclear progesterone receptors was markedly increased.

UI MeSH Term Description Entries
D011182 Postoperative Care The period of care beginning when the patient is removed from surgery and aimed at meeting the patient's psychological and physical needs directly after surgery. (From Dictionary of Health Services Management, 2d ed) Care, Postoperative,Postoperative Procedures,Procedures, Postoperative,Postoperative Procedure,Procedure, Postoperative
D011245 Pregnadienes Pregnane derivatives containing two double bonds anywhere within the ring structures.
D011960 Receptors, Estrogen Cytoplasmic proteins that bind estrogens and migrate to the nucleus where they regulate DNA transcription. Evaluation of the state of estrogen receptors in breast cancer patients has become clinically important. Estrogen Receptor,Estrogen Receptors,Estrogen Nuclear Receptor,Estrogen Receptor Type I,Estrogen Receptor Type II,Estrogen Receptors Type I,Estrogen Receptors Type II,Receptor, Estrogen Nuclear,Receptors, Estrogen, Type I,Receptors, Estrogen, Type II,Nuclear Receptor, Estrogen,Receptor, Estrogen
D011980 Receptors, Progesterone Specific proteins found in or on cells of progesterone target tissues that specifically combine with progesterone. The cytosol progesterone-receptor complex then associates with the nucleic acids to initiate protein synthesis. There are two kinds of progesterone receptors, A and B. Both are induced by estrogen and have short half-lives. Progesterone Receptors,Progestin Receptor,Progestin Receptors,Receptor, Progesterone,Receptors, Progestin,Progesterone Receptor,Receptor, Progestin
D003613 Danazol A synthetic steroid with antigonadotropic and anti-estrogenic activities that acts as an anterior pituitary suppressant by inhibiting the pituitary output of gonadotropins. It possesses some androgenic properties. Danazol has been used in the treatment of endometriosis and some benign breast disorders. Azol,Cyclomen,Danatrol,Danazant,Danazol-Ratiopharm,Danocrine,Danol,Danoval,Ladogal,Norciden,Panacrine,Danazol Ratiopharm
D004717 Endometrium The mucous membrane lining of the uterine cavity that is hormonally responsive during the MENSTRUAL CYCLE and PREGNANCY. The endometrium undergoes cyclic changes that characterize MENSTRUATION. After successful FERTILIZATION, it serves to sustain the developing embryo. Endometria
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D013997 Time Factors Elements of limited time intervals, contributing to particular results or situations. Time Series,Factor, Time,Time Factor

Related Publications

L V Adamian, and M L Alekseeva, and N N Zhukova, and L S Minina, and E A Novikov
January 2022, Frontiers in endocrinology,
L V Adamian, and M L Alekseeva, and N N Zhukova, and L S Minina, and E A Novikov
April 1982, The Journal of reproductive medicine,
L V Adamian, and M L Alekseeva, and N N Zhukova, and L S Minina, and E A Novikov
January 1979, Advances in experimental medicine and biology,
L V Adamian, and M L Alekseeva, and N N Zhukova, and L S Minina, and E A Novikov
January 2004, Acta histochemica,
L V Adamian, and M L Alekseeva, and N N Zhukova, and L S Minina, and E A Novikov
December 1979, The Journal of clinical endocrinology and metabolism,
L V Adamian, and M L Alekseeva, and N N Zhukova, and L S Minina, and E A Novikov
April 1990, Nihon Gan Chiryo Gakkai shi,
L V Adamian, and M L Alekseeva, and N N Zhukova, and L S Minina, and E A Novikov
August 1979, European journal of obstetrics, gynecology, and reproductive biology,
L V Adamian, and M L Alekseeva, and N N Zhukova, and L S Minina, and E A Novikov
November 1993, Pathology, research and practice,
L V Adamian, and M L Alekseeva, and N N Zhukova, and L S Minina, and E A Novikov
July 1987, Akusherstvo i ginekologiia,
L V Adamian, and M L Alekseeva, and N N Zhukova, and L S Minina, and E A Novikov
February 1989, Akusherstvo i ginekologiia,
Copied contents to your clipboard!