Experimental transmission of jaagsiekte (ovine pulmonary adenomatosis) to goats. 1988

R C Tustin, and A L Williamson, and D F York, and D W Verwoerd
Faculty of Veterinary Science, University of Pretoria, Private Bag, Onderstepoort.

Jaagsiekte was successfully transmitted to at least 2 out of 6 goats inoculated intratracheally with partially purified jaagsiekte retrovirus. Multiple, small, well circumscribed nodules found in the lungs consisted of typical papilliform proliferations of neoplastic Type II epithelial cells. Histological evidence of a mild interstitial pneumonia in 4 of the experimental animals can probably be attributed to a contaminating lentivirus in the jaagsiekte retrovirus preparation, as suggested by the seroconversion of the animals.

UI MeSH Term Description Entries
D008168 Lung Either of the pair of organs occupying the cavity of the thorax that effect the aeration of the blood. Lungs
D011648 Pulmonary Adenomatosis, Ovine A contagious, neoplastic, pulmonary disease of sheep characterized by hyperplasia and hypertrophy of pneumocytes and epithelial cells of the lung. It is caused by JAAGSIEKTE SHEEP RETROVIRUS. Adenomatosis, Pulmonary, Ovine,Carcinoma, Ovine Pulmonary,Jaagsiekte,Adenomatosis, Ovine Pulmonary,Ovine Pulmonary Adenomatosis,Ovine Pulmonary Carcinoma,Pulmonary Ovine Adenomatosis,Adenomatoses, Ovine Pulmonary,Adenomatoses, Pulmonary Ovine,Adenomatosis, Pulmonary Ovine,Carcinomas, Ovine Pulmonary,Ovine Adenomatoses, Pulmonary,Ovine Adenomatosis, Pulmonary,Ovine Pulmonary Adenomatoses,Ovine Pulmonary Carcinomas,Pulmonary Adenomatoses, Ovine,Pulmonary Carcinoma, Ovine,Pulmonary Carcinomas, Ovine,Pulmonary Ovine Adenomatoses
D006041 Goats Any of numerous agile, hollow-horned RUMINANTS of the genus Capra, in the family Bovidae, closely related to the SHEEP. Capra,Capras,Goat
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D000831 Animals, Newborn Refers to animals in the period of time just after birth. Animals, Neonatal,Animal, Neonatal,Animal, Newborn,Neonatal Animal,Neonatal Animals,Newborn Animal,Newborn Animals
D012756 Sheep Any of the ruminant mammals with curved horns in the genus Ovis, family Bovidae. They possess lachrymal grooves and interdigital glands, which are absent in GOATS. Ovis,Sheep, Dall,Dall Sheep,Ovis dalli

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