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In association with treatment for pharyngitis, a 47-year-old white man developed a systemic illness with fever, myalgia, episcleritis, hemoptysis, pleurisy, eosinophilia, and renal impairment. Renal biopsy revealed granulomatous interstitial nephritis, which resolved due to no specific treatment other than withdrawing all medication. Both the severe systemic manifestations and spontaneous recovery are unusual in association with drug-induced granulomatous nephritis. The drugs that may have caused the reaction included dihydrocodeine, phenylpropanolamine, erythromycin, and amoxycillin. Although the latter three drugs have been previously implicated in the development of interstitial nephritis, there have been no previous reports of granulomatous interstitial nephritis with any of these drugs.
D R Singer, and
J G Simpson, and
G R Catto, and
A W Johnston
October 1997,
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D R Singer, and
J G Simpson, and
G R Catto, and
A W Johnston
January 1983,
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D R Singer, and
J G Simpson, and
G R Catto, and
A W Johnston
February 2012,
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D R Singer, and
J G Simpson, and
G R Catto, and
A W Johnston
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D R Singer, and
J G Simpson, and
G R Catto, and
A W Johnston
March 2023,
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D R Singer, and
J G Simpson, and
G R Catto, and
A W Johnston
January 1984,
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D R Singer, and
J G Simpson, and
G R Catto, and
A W Johnston
March 2007,
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D R Singer, and
J G Simpson, and
G R Catto, and
A W Johnston
January 1997,
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D R Singer, and
J G Simpson, and
G R Catto, and
A W Johnston
February 2013,
Clinical and experimental nephrology,
D R Singer, and
J G Simpson, and
G R Catto, and
A W Johnston
December 1995,
Human pathology,
