Biomaterial Database

Digestive motor patterns and transit of luminal contents in canine ileum. 1988

M L Siegle, and H J Ehrlein

Institute of Zoophysiology, University of Hohenhein, Stuttgart, Federal Republic of Germany.

In the present study ileal motor patterns caused by orally administered noncaloric and nutrient meals were investigated. Effects of nutrients were additionally elucidated by an ileal infusion of nutrients. Conscious dogs equipped with closely spaced extraluminal transducers were used. Motor patterns were quantified by a computerized method. Transit rates were measured fluoroscopically. Compared with the motor pattern caused by the noncaloric meal, the nutrient meal diminished the number of contractions from 11.7 to 5.9/min, reduced the incidence of contraction waves from 70.8 to 39.4%, shortened the length of contraction spread from 4.0 to 1.4 cm, and slowed the transit rate from 18.4 to 3.2 cm/min. Ileal infusion of nutrients induced a motor pattern similar to that of the nutrient meal. The transit rate correlated with the length of contraction spread (r = 0.75), the ratio between contraction waves and stationary contractions (r = 0.77), and the number of contractions (r = 0.69). The length of contraction spread was the most characteristic feature of motor patterns and the most important factor influencing transit.

UI	MeSH Term	Description	Entries
D007082	Ileum	The distal and narrowest portion of the SMALL INTESTINE, between the JEJUNUM and the ILEOCECAL VALVE of the LARGE INTESTINE.
D009119	Muscle Contraction	A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.	Inotropism,Muscular Contraction,Contraction, Muscle,Contraction, Muscular,Contractions, Muscle,Contractions, Muscular,Inotropisms,Muscle Contractions,Muscular Contractions
D009130	Muscle, Smooth	Unstriated and unstriped muscle, one of the muscles of the internal organs, blood vessels, hair follicles, etc. Contractile elements are elongated, usually spindle-shaped cells with centrally located nuclei. Smooth muscle fibers are bound together into sheets or bundles by reticular fibers and frequently elastic nets are also abundant. (From Stedman, 25th ed)	Muscle, Involuntary,Smooth Muscle,Involuntary Muscle,Involuntary Muscles,Muscles, Involuntary,Muscles, Smooth,Smooth Muscles
D004063	Digestion	The process of breakdown of food for metabolism and use by the body.
D004285	Dogs	The domestic dog, Canis familiaris, comprising about 400 breeds, of the carnivore family CANIDAE. They are worldwide in distribution and live in association with people. (Walker's Mammals of the World, 5th ed, p1065)	Canis familiaris,Dog
D004435	Eating	The consumption of edible substances.	Dietary Intake,Feed Intake,Food Intake,Macronutrient Intake,Micronutrient Intake,Nutrient Intake,Nutritional Intake,Ingestion,Dietary Intakes,Feed Intakes,Intake, Dietary,Intake, Feed,Intake, Food,Intake, Macronutrient,Intake, Micronutrient,Intake, Nutrient,Intake, Nutritional,Macronutrient Intakes,Micronutrient Intakes,Nutrient Intakes,Nutritional Intakes
D005260	Female		Females
D005766	Gastrointestinal Contents	The contents included in all or any segment of the GASTROINTESTINAL TRACT.	Digestive Tract Contents,Intestinal Contents,Stomach Contents,GI Contents,Digestive Tract Content,GI Content,Gastrointestinal Content,Intestinal Content,Stomach Content
D005772	Gastrointestinal Transit	Passage of food (sometimes in the form of a test meal) through the gastrointestinal tract as measured in minutes or hours. The rate of passage through the intestine is an indicator of small bowel function.	GI Transit,GI Transits,Gastrointestinal Transits,Transit, GI,Transit, Gastrointestinal,Transits, GI,Transits, Gastrointestinal
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia