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Molecular Epidemiology of Group A Streptococcus Infections in The Gambia. 2021
Sona Jabang, and
Annette Erhart, and
Saffiatou Darboe, and
Aru-Kumba Baldeh, and
Valerie Delforge, and
Gabriella Watson, and
Ebenezer Foster-Nyarko, and
Rasheed Salaudeen, and
Bolarinde Lawal, and
Grant Mackenzie, and
Anne Botteaux, and
Martin Antonio, and
Pierre R Smeesters, and
On Behalf Of The Mrcg StrepA Study Group
Medical Research Council Unit The Gambia at the London School of Hygiene and Tropical Medicine, Banjul 273, The Gambia.
Molecular epidemiological data on Group A Streptococcus (GAS) infection in Africa is scarce. We characterized the emm-types and emm-clusters of 433 stored clinical GAS isolates from The Gambia collected between 2004 and 2018. To reduce the potential for strain mistyping, we used a newly published primer for emm-typing. There was considerable strain diversity, highlighting the need for vaccine development offering broad strain protection.
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