BIOMAT Database Logo BIOMAT Database Logo

Equine ehrlichial colitis: effect of oxytetracycline treatment during the incubation period of Ehrlichia risticii infection in ponies. 1988

J E Palmer, and R H Whitlock, and C E Benson
Department of Clinical Studies, School of Veterinary Medicine, University of Pennsylvania, Kennett Square 19348.

Equine ehrlichial colitis was experimentally induced in 18 ponies, using Ehrlichia risticii-infected blood. Four ponies (group 1) were treated with oxytetracycline (6.6 mg/kg of body weight, IV, q 12 h), beginning 14 hours before inoculation and continuing for 5 days after inoculation. Four additional ponies (group 2) were treated similarly for 10 days after inoculation. The remaining 10 ponies were used as nontreated, infected controls. Clinical disease was delayed in 3 group-1 ponies and in 4 group-2 ponies. Protective immunity developed in the remaining pony that did not develop clinical disease and in 1 group-1 pony and 2 group-2 ponies that developed mild, transient clinical signs.

UI MeSH Term Description Entries
D010118 Oxytetracycline A TETRACYCLINE analog isolated from the actinomycete STREPTOMYCES RIMOSUS and used in a wide variety of clinical conditions. Hydroxytetracycline,Bisolvomycin,Geomycin,Oxyterracin,Oxyterracine,Oxytetracid,Oxytetracycline Anhydrous,Oxytetracycline Calcium,Oxytetracycline Dihydrate,Oxytetracycline Hydrochloride,Oxytetracycline Monohydrochloride,Oxytetracycline Sulfate (2:1),Oxytetracycline, (4a beta,5 beta,5a beta,12a beta)-Isomer,Oxytetracycline, (5 beta)-Isomer,Oxytetracycline, Anhydrous,Oxytetracycline, Calcium (1:1) Salt,Oxytetracycline, Disodium Salt, Dihydrate,Oxytetracycline, Sodium Salt,Terramycin
D003092 Colitis Inflammation of the COLON section of the large intestine (INTESTINE, LARGE), usually with symptoms such as DIARRHEA (often with blood and mucus), ABDOMINAL PAIN, and FEVER. Colitides
D004536 Ehrlichia Small, often pleomorphic, coccoid to ellipsoidal organisms occurring intracytoplasmically in circulating LYMPHOCYTES. They are the etiologic agents of tick-borne diseases of humans; DOGS; CATTLE; SHEEP; GOATS; and HORSES. Cowdria,Ehrlichia ewingii
D006734 Horse Diseases Diseases of domestic and wild horses of the species Equus caballus. Equine Diseases,Disease, Equine,Disease, Horse,Diseases, Equine,Diseases, Horse,Equine Disease,Horse Disease
D006736 Horses Large, hoofed mammals of the family EQUIDAE. Horses are active day and night with most of the day spent seeking and consuming food. Feeding peaks occur in the early morning and late afternoon, and there are several daily periods of rest. Equus caballus,Equus przewalskii,Horse, Domestic,Domestic Horse,Domestic Horses,Horse,Horses, Domestic
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D012288 Rickettsiaceae Infections Infections with bacteria of the family RICKETTSIACEAE. Infections, Rickettsiaceae,Infection, Rickettsiaceae,Rickettsiaceae Infection

Related Publications

J E Palmer, and R H Whitlock, and C E Benson
Effect of treatment with erythromycin and rifampin during the acute stages of experimentally induced equine ehrlichial colitis in ponies.
November 1992, American journal of veterinary research,
J E Palmer, and R H Whitlock, and C E Benson
Evaluation of fetal infection and abortion in pregnant ponies experimentally infected with Ehrlichia risticii.
October 1995, American journal of veterinary research,
J E Palmer, and R H Whitlock, and C E Benson
Serological response of experimental ponies orally infected with Ehrlichia risticii.
June 1989, Equine veterinary journal. Supplement,
J E Palmer, and R H Whitlock, and C E Benson
Clinical, histopathological, and immunological responses of ponies to Ehrlichia sennetsu and subsequent Ehrlichia risticii challenge.
November 1988, Infection and immunity,
J E Palmer, and R H Whitlock, and C E Benson
Susceptibility of cats to infection with Ehrlichia risticii, causative agent of equine monocytic ehrlichiosis.
December 1988, American journal of veterinary research,
J E Palmer, and R H Whitlock, and C E Benson
Ehrlichial infection in Cameroonian canines by Ehrlichia canis and Ehrlichia ewingii.
November 2005, Veterinary microbiology,
J E Palmer, and R H Whitlock, and C E Benson
Identification of Ehrlichia risticii as the causative agent of two equine abortions following natural maternal infection.
April 1995, Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc,
J E Palmer, and R H Whitlock, and C E Benson
Susceptibility of dogs to infection with Ehrlichia risticii, causative agent of equine monocytic ehrlichiosis (Potomac horse fever).
September 1988, American journal of veterinary research,
J E Palmer, and R H Whitlock, and C E Benson
Lack of lysosomal fusion with phagosomes containing Ehrlichia risticii in P388D1 cells: abrogation of inhibition with oxytetracycline.
December 1988, Infection and immunity,
J E Palmer, and R H Whitlock, and C E Benson
Two cases of Neorickettsia (Ehrlichia) risticii infection in horses from Nova Scotia.
May 2004, The Canadian veterinary journal = La revue veterinaire canadienne,
Copied contents to your clipboard!