| D007668 |
Kidney |
Body organ that filters blood for the secretion of URINE and that regulates ion concentrations. |
Kidneys |
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| D008099 |
Liver |
A large lobed glandular organ in the abdomen of vertebrates that is responsible for detoxification, metabolism, synthesis and storage of various substances. |
Livers |
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| D011339 |
Probenecid |
The prototypical uricosuric agent. It inhibits the renal excretion of organic anions and reduces tubular reabsorption of urate. Probenecid has also been used to treat patients with renal impairment, and, because it reduces the renal tubular excretion of other drugs, has been used as an adjunct to antibacterial therapy. |
Benecid,Benemid,Benuryl,Pro-Cid,Probecid,Probenecid Weimer |
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| D000818 |
Animals |
Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. |
Animal,Metazoa,Animalia |
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| D001692 |
Biological Transport |
The movement of materials (including biochemical substances and drugs) through a biological system at the cellular level. The transport can be across cell membranes and epithelial layers. It also can occur within intracellular compartments and extracellular compartments. |
Transport, Biological,Biologic Transport,Transport, Biologic |
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| D051381 |
Rats |
The common name for the genus Rattus. |
Rattus,Rats, Laboratory,Rats, Norway,Rattus norvegicus,Laboratory Rat,Laboratory Rats,Norway Rat,Norway Rats,Rat,Rat, Laboratory,Rat, Norway,norvegicus, Rattus |
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| D022781 |
Hepatocytes |
The main structural component of the LIVER. They are specialized EPITHELIAL CELLS that are organized into interconnected plates called lobules. |
Hepatic Cells,Cell, Hepatic,Cells, Hepatic,Hepatic Cell,Hepatocyte |
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| D027361 |
Organic Anion Transporters |
Proteins involved in the transport of organic anions. They play an important role in the elimination of a variety of endogenous substances, xenobiotics and their metabolites from the body. |
Membrane Transport Proteins, Organic Anion,OAT Transport Protein,OATP Transporter,Organic Anion Transport Polypeptide,Organic Anion Transport Polypeptides,Organic Anion Transport Protein,Organic Anion Transporter,OAT Transport Proteins,OATP Proteins,OATP Transporters,Organic Anion Transport Proteins,Anion Transporter, Organic,Anion Transporters, Organic,Protein, OAT Transport,Transport Protein, OAT,Transport Proteins, OAT,Transporter, OATP,Transporter, Organic Anion,Transporters, OATP,Transporters, Organic Anion |
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| D027381 |
Liver-Specific Organic Anion Transporter 1 |
An organic anion transporter found in human and mouse liver. It is capable of transporting a variety organic anions and mediates sodium-independent uptake of bile in the liver. |
LST-1 Transport Protein,Organic Anion Transport Polypeptide C,Liver-Specific Organic Anion Transporter, LST-1,Oatp-C Transport Protein,SLC21A6 Transporter,Solute Carrier Family-21(Organic Anion Transporter), Member 6 Protein,LST 1 Transport Protein,Liver Specific Organic Anion Transporter 1,Liver Specific Organic Anion Transporter, LST 1,Oatp C Transport Protein,Transport Protein, LST-1,Transport Protein, Oatp-C,Transporter, SLC21A6 |
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| D029362 |
Organic Anion Transporters, Sodium-Independent |
A subclass of ORGANIC ANION TRANSPORTERS that do not rely directly or indirectly upon sodium ion gradients for the transport of organic ions. |
Sodium-Independent Organic Anion Transporters,Organic Anion Transporters, Sodium Independent,Sodium Independent Organic Anion Transporters |
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