Biomaterial Database

The effect of nalbuphine on the common bile duct pressure. 1988

J L Butsch, and J A Okoli

State University of N.Y. Medical School, Buffalo.

The effect of Nalbuphine on the common bile duct pressure of ten women who had cholecystectomy and common duct exploration for cholelithiasis and choledocholithiasis was studied. In this pilot study, intravenously inject Nalbuphine (20 mg) significantly raised the common duct pressure (P less than 0.01). However, none of the patients experienced pain as a result of the elevation in the biliary pressure; there was no deleterious cardiopulmonary effect.

UI	MeSH Term	Description	Entries
D008875	Middle Aged	An adult aged 45 - 64 years.	Middle Age
D009019	Morphinans	Compounds based on a partially saturated iminoethanophenanthrene, which can be described as ethylimino-bridged benzo-decahydronaphthalenes. They include some of the OPIOIDS found in PAPAVER that are used as ANALGESICS.	Morphinan
D009266	Nalbuphine	A narcotic used as a pain medication. It appears to be an agonist at KAPPA RECEPTORS and an antagonist or partial agonist at MU RECEPTORS.	EN-2234A,Nalbuphine Hydrochloride,Nalbuphine Serb,Nubain,EN 2234A,EN2234A
D011312	Pressure	A type of stress exerted uniformly in all directions. Its measure is the force exerted per unit area. (McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)	Pressures
D003135	Common Bile Duct	The largest bile duct. It is formed by the junction of the CYSTIC DUCT and the COMMON HEPATIC DUCT.	Choledochus,Bile Duct, Common,Common Bile Ducts,Duct, Common Bile
D005260	Female		Females
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328	Adult	A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available.	Adults
D000368	Aged	A person 65 years of age or older. For a person older than 79 years, AGED, 80 AND OVER is available.	Elderly